First true blood pressure measurement with micropulse detection of arterial opening achieved
Abstract There is a well-accepted need for a new more accurate solution to automatic blood pressure measurement, in spite of clinical convenience continuing to encourage the adoption of oscillometric devices with their known poor accuracy throughout healthcare. Our solution avoids estimates, mathema...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-87855-2 |
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| author | Alan Murray Dingchang Zheng Clive J. Griffiths Chengyu Liu David J. Graham Jeff Neasham Adrian J. Cossor |
| author_facet | Alan Murray Dingchang Zheng Clive J. Griffiths Chengyu Liu David J. Graham Jeff Neasham Adrian J. Cossor |
| author_sort | Alan Murray |
| collection | DOAJ |
| description | Abstract There is a well-accepted need for a new more accurate solution to automatic blood pressure measurement, in spite of clinical convenience continuing to encourage the adoption of oscillometric devices with their known poor accuracy throughout healthcare. Our solution avoids estimates, mathematical modelling, oscillometric algorithms, and inadequate calibration against numerous private clinical data sets. Here we show that our new technique detects, from an arm cuff, micropulses associated with arterial opening between systolic and diastolic pressures; hence detecting systole at the first micropulse and diastole at the last, during cuff deflation. Our technique has equivalent accuracy to the gold standard auscultatory method, and is significantly better than the requirements of the current international standard for blood pressure devices. Our results provide scientific evidence for the effectiveness of our technique, and demonstrate significant clinically important improvements. We anticipate that our technique can be automated easily and economically. We acknowledge that this early study is an initial manual evaluation, but expect this new technique to be an automated universal solution for true blood pressure measurement, and a vital step change in an important clinical measurement in healthcare of the worldwide population. |
| format | Article |
| id | doaj-art-a49a50c1035f44c7b64dbeb13402aace |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-a49a50c1035f44c7b64dbeb13402aace2025-02-02T12:16:39ZengNature PortfolioScientific Reports2045-23222025-01-011511810.1038/s41598-025-87855-2First true blood pressure measurement with micropulse detection of arterial opening achievedAlan Murray0Dingchang Zheng1Clive J. Griffiths2Chengyu Liu3David J. Graham4Jeff Neasham5Adrian J. Cossor6Engineering School & Medical Faculty, Newcastle UniversityCentre for Intelligent Healthcare, Coventry UniversityEngineering School & Medical Faculty, Newcastle UniversitySchool of Instrument Science and Engineering, Southeast UniversityEngineering School & Medical Faculty, Newcastle UniversityEngineering School & Medical Faculty, Newcastle UniversityA C Cossor & Son (Technology) LtdAbstract There is a well-accepted need for a new more accurate solution to automatic blood pressure measurement, in spite of clinical convenience continuing to encourage the adoption of oscillometric devices with their known poor accuracy throughout healthcare. Our solution avoids estimates, mathematical modelling, oscillometric algorithms, and inadequate calibration against numerous private clinical data sets. Here we show that our new technique detects, from an arm cuff, micropulses associated with arterial opening between systolic and diastolic pressures; hence detecting systole at the first micropulse and diastole at the last, during cuff deflation. Our technique has equivalent accuracy to the gold standard auscultatory method, and is significantly better than the requirements of the current international standard for blood pressure devices. Our results provide scientific evidence for the effectiveness of our technique, and demonstrate significant clinically important improvements. We anticipate that our technique can be automated easily and economically. We acknowledge that this early study is an initial manual evaluation, but expect this new technique to be an automated universal solution for true blood pressure measurement, and a vital step change in an important clinical measurement in healthcare of the worldwide population.https://doi.org/10.1038/s41598-025-87855-2Blood pressure measurementBlood pressure accuracyBlood pressure physiologyCalibrationInternational standardsAuscultation |
| spellingShingle | Alan Murray Dingchang Zheng Clive J. Griffiths Chengyu Liu David J. Graham Jeff Neasham Adrian J. Cossor First true blood pressure measurement with micropulse detection of arterial opening achieved Scientific Reports Blood pressure measurement Blood pressure accuracy Blood pressure physiology Calibration International standards Auscultation |
| title | First true blood pressure measurement with micropulse detection of arterial opening achieved |
| title_full | First true blood pressure measurement with micropulse detection of arterial opening achieved |
| title_fullStr | First true blood pressure measurement with micropulse detection of arterial opening achieved |
| title_full_unstemmed | First true blood pressure measurement with micropulse detection of arterial opening achieved |
| title_short | First true blood pressure measurement with micropulse detection of arterial opening achieved |
| title_sort | first true blood pressure measurement with micropulse detection of arterial opening achieved |
| topic | Blood pressure measurement Blood pressure accuracy Blood pressure physiology Calibration International standards Auscultation |
| url | https://doi.org/10.1038/s41598-025-87855-2 |
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