Phosphatidylinositol promoted the proliferation and invasion of pituitary adenoma cells by regulating POU1F1 expression

Phosphatidylinositol promoted the proliferation and invasion of pituitary adenoma cells by regulating POU1F1 expression

Abstract Invasiveness of pituitary adenoma is the main cause of its poor prognosis, mechanism of which remains largely unknown. In this study, the differential proteins between invasive and non-invasive pituitary tumors (IPA and NIPA) were identified by TMT labeled quantitative proteomics. The diffe...

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Bibliographic Details
Main Authors: Tongjiang Xu, Xiaodong Zhai, RuiWei Wang, Xiaoben Wu, ZhiZhen Zhou, MiaoMiao Shang, Chongcheng Wang, Tengfei Qi, Wei Yang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cancer & Metabolism
Subjects:
Metabolomic
Phosphatidylinositol
PITPNM1
Pituitary tumor
POU1F1
Proteomic
Online Access:https://doi.org/10.1186/s40170-024-00372-0
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