Interleukin-7 and Immunosenescence
The age of an individual is an important, independent risk factor for many of the most common diseases afflicting modern societies. Interleukin-7 (IL-7) plays a central, critical role in the homeostasis of the immune system. Recent studies support a critical role for IL-7 in the maintenance of a vig...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2017/4807853 |
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| _version_ | 1832548072161280000 |
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| author | Vanloan Nguyen Andrew Mendelsohn James W. Larrick |
| author_facet | Vanloan Nguyen Andrew Mendelsohn James W. Larrick |
| author_sort | Vanloan Nguyen |
| collection | DOAJ |
| description | The age of an individual is an important, independent risk factor for many of the most common diseases afflicting modern societies. Interleukin-7 (IL-7) plays a central, critical role in the homeostasis of the immune system. Recent studies support a critical role for IL-7 in the maintenance of a vigorous healthspan. We describe the role of IL-7 and its receptor in immunosenescence, the aging of the immune system. An understanding of the role that IL-7 plays in aging may permit parsimonious preventative or therapeutic solutions for diverse conditions. Perhaps IL-7 might be used to “tune” the immune system to optimize human healthspan and longevity. |
| format | Article |
| id | doaj-art-a4775f8702654767b3cfeaabf56686dd |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-a4775f8702654767b3cfeaabf56686dd2025-02-03T06:42:16ZengWileyJournal of Immunology Research2314-88612314-71562017-01-01201710.1155/2017/48078534807853Interleukin-7 and ImmunosenescenceVanloan Nguyen0Andrew Mendelsohn1James W. Larrick2Panorama Research Institute, 1230 Bordeaux Drive, Sunnyvale, CA 94089, USAPanorama Research Institute, 1230 Bordeaux Drive, Sunnyvale, CA 94089, USAPanorama Research Institute, 1230 Bordeaux Drive, Sunnyvale, CA 94089, USAThe age of an individual is an important, independent risk factor for many of the most common diseases afflicting modern societies. Interleukin-7 (IL-7) plays a central, critical role in the homeostasis of the immune system. Recent studies support a critical role for IL-7 in the maintenance of a vigorous healthspan. We describe the role of IL-7 and its receptor in immunosenescence, the aging of the immune system. An understanding of the role that IL-7 plays in aging may permit parsimonious preventative or therapeutic solutions for diverse conditions. Perhaps IL-7 might be used to “tune” the immune system to optimize human healthspan and longevity.http://dx.doi.org/10.1155/2017/4807853 |
| spellingShingle | Vanloan Nguyen Andrew Mendelsohn James W. Larrick Interleukin-7 and Immunosenescence Journal of Immunology Research |
| title | Interleukin-7 and Immunosenescence |
| title_full | Interleukin-7 and Immunosenescence |
| title_fullStr | Interleukin-7 and Immunosenescence |
| title_full_unstemmed | Interleukin-7 and Immunosenescence |
| title_short | Interleukin-7 and Immunosenescence |
| title_sort | interleukin 7 and immunosenescence |
| url | http://dx.doi.org/10.1155/2017/4807853 |
| work_keys_str_mv | AT vanloannguyen interleukin7andimmunosenescence AT andrewmendelsohn interleukin7andimmunosenescence AT jameswlarrick interleukin7andimmunosenescence |