ER-PM membrane contact site regulation by yeast ORPs and membrane stress pathways.

In yeast, at least seven proteins (Ice2p, Ist2p, Scs2/22p, Tcb1-Tcb3p) affect cortical endoplasmic reticulum (ER) tethering and contact with the plasma membrane (PM). In Δ-super-tether (Δ-s-tether) cells that lack these tethers, cortical ER-PM association is all but gone. Yeast OSBP homologue (Osh)...

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Bibliographic Details
Main Authors: Evan Quon, Aleksa Nenadic, Mohammad F Zaman, Jesper Johansen, Christopher T Beh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010106&type=printable
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