Hochuekkito accelerates recovery from cisplatin induced-muscle atrophy accompanied by slow-twitch fiber-specific microRNA upregulation in mice

Hochuekkito accelerates recovery from cisplatin induced-muscle atrophy accompanied by slow-twitch fiber-specific microRNA upregulation in mice

IntroductionCis-diamine-dichloro-platinum (II) (cisplatin) is a widely prescribed anticancer drug known to induce severe side effects, including skeletal muscle atrophy. As muscle atrophy negatively impacts the prognosis and survival of cancer patients, elucidation of its pathogenesis and developmen...

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Bibliographic Details
Main Authors: Hitomi Sekine, Chinami Matsumoto, Naoki Fujitsuka, Sachiko Mogami, Shunsuke Ohnishi, Hiroshi Takeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
cisplatin
muscle atrophy
hochuekkito
myogenesis
differentiation
regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1502563/full
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