Development of a DNA Aptamer‐Based Approach to Noninvasively Image CAR‐T Cells In Vivo and Traceless Enrichment In Vitro

Development of a DNA Aptamer‐Based Approach to Noninvasively Image CAR‐T Cells In Vivo and Traceless Enrichment In Vitro

Abstract Chimeric antigen receptor (CAR) T cells offered a potential cure for malignancies, however, their outcomes and dynamics across different anatomical sites remained inadequately characterized. Monitoring the bio‐distribution and tumor‐homing of CAR‐T cells in vivo is crucial, as it provides p...

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Bibliographic Details
Main Authors: Minghui Chen, Pengzhao Chang, Zhen Zhang, Dan Liu, Rui Hou, Ming Shi, Jingjing Li, Kai Xu, Junnian Zheng
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
Subjects:
CAR‐T cells
DNA aptamers
enrichment
fluorescence imaging
tracking
Online Access:https://doi.org/10.1002/advs.202506746
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