Mechanistic Insight into the Enhanced Anti-Pulmonary Hypertension Efficacy of Wogonin Co-Amorphous

Mechanistic Insight into the Enhanced Anti-Pulmonary Hypertension Efficacy of Wogonin Co-Amorphous

<b>Background:</b> Pulmonary hypertension (PH) remains a life-threatening rare disease characterized by inflammation and oxidative stress in pulmonary artery smooth muscle cells (PASMCs). Wogonin (Wog), a plant-derived polyphenolic compound extracted from <i>Scutellaria baicalensis...

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Bibliographic Details
Main Authors: Zhongshui Xie, Yucai Chen, Jiaqi Xie, Yan Lei, Chunxue Jia, Yulu Liang, Hongjuan Wang, Jianmei Huang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceutics
Subjects:
wogonin
solubility
co-amorphous
oxidative stress
pulmonary hypertension
Online Access:https://www.mdpi.com/1999-4923/17/6/724
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