Polymers for Fabricating Nerve Conduits

Peripheral nerve regeneration is a complicated and long-term medical challenge that requires suitable guides for bridging nerve injury gaps and restoring nerve functions. Many natural and synthetic polymers have been used to fabricate nerve conduits as well as luminal fillers for achieving desired n...

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Main Authors: Shanfeng Wang, Lei Cai
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2010/138686
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author Shanfeng Wang
Lei Cai
author_facet Shanfeng Wang
Lei Cai
author_sort Shanfeng Wang
collection DOAJ
description Peripheral nerve regeneration is a complicated and long-term medical challenge that requires suitable guides for bridging nerve injury gaps and restoring nerve functions. Many natural and synthetic polymers have been used to fabricate nerve conduits as well as luminal fillers for achieving desired nerve regenerative functions. It is important to understand the intrinsic properties of these polymers and techniques that have been used for fabricating nerve conduits. Previously extensive reviews have been focused on the biological functions and in vivo performance of polymeric nerve conduits. In this paper, we emphasize on the structures, thermal and mechanical properties of these naturally derived synthetic polymers, and their fabrication methods. These aspects are critical for the performance of fabricated nerve conduits. By learning from the existing candidates, we can advance the strategies for designing novel polymeric systems with better properties for nerve regeneration.
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institution Kabale University
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publishDate 2010-01-01
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record_format Article
series International Journal of Polymer Science
spelling doaj-art-a4164d469a974799bd9161d4bd566a6a2025-02-03T05:52:18ZengWileyInternational Journal of Polymer Science1687-94221687-94302010-01-01201010.1155/2010/138686138686Polymers for Fabricating Nerve ConduitsShanfeng Wang0Lei Cai1Department of Materials Science and Engineering, The University of Tennessee, Knoxville, TN 37996, USADepartment of Materials Science and Engineering, The University of Tennessee, Knoxville, TN 37996, USAPeripheral nerve regeneration is a complicated and long-term medical challenge that requires suitable guides for bridging nerve injury gaps and restoring nerve functions. Many natural and synthetic polymers have been used to fabricate nerve conduits as well as luminal fillers for achieving desired nerve regenerative functions. It is important to understand the intrinsic properties of these polymers and techniques that have been used for fabricating nerve conduits. Previously extensive reviews have been focused on the biological functions and in vivo performance of polymeric nerve conduits. In this paper, we emphasize on the structures, thermal and mechanical properties of these naturally derived synthetic polymers, and their fabrication methods. These aspects are critical for the performance of fabricated nerve conduits. By learning from the existing candidates, we can advance the strategies for designing novel polymeric systems with better properties for nerve regeneration.http://dx.doi.org/10.1155/2010/138686
spellingShingle Shanfeng Wang
Lei Cai
Polymers for Fabricating Nerve Conduits
International Journal of Polymer Science
title Polymers for Fabricating Nerve Conduits
title_full Polymers for Fabricating Nerve Conduits
title_fullStr Polymers for Fabricating Nerve Conduits
title_full_unstemmed Polymers for Fabricating Nerve Conduits
title_short Polymers for Fabricating Nerve Conduits
title_sort polymers for fabricating nerve conduits
url http://dx.doi.org/10.1155/2010/138686
work_keys_str_mv AT shanfengwang polymersforfabricatingnerveconduits
AT leicai polymersforfabricatingnerveconduits