Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy
The study aimed to uncover the risk factors for the new defined pancreatic fistula (PF) and clinical related PF (CR-PF) after pancreaticoduodenectomy (PD) surgery and to evaluate the medico-economic effect of patients. A total of 412 patients were classified into two groups according to different cr...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2015/917689 |
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| _version_ | 1832552377660473344 |
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| author | Renping Huang Bing Liu Hua Chen Xuewei Bai Rui Kong Gang Wang Yongwei Wang Bei Sun Yinghui Guan |
| author_facet | Renping Huang Bing Liu Hua Chen Xuewei Bai Rui Kong Gang Wang Yongwei Wang Bei Sun Yinghui Guan |
| author_sort | Renping Huang |
| collection | DOAJ |
| description | The study aimed to uncover the risk factors for the new defined pancreatic fistula (PF) and clinical related PF (CR-PF) after pancreaticoduodenectomy (PD) surgery and to evaluate the medico-economic effect of patients. A total of 412 patients were classified into two groups according to different criteria, PF and NOPF according to PF occurrence: CR-PF (grades B and C) and NOCR-PF (grade A) based on PF severity. A total of 28 factors were evaluated by univariate and multivariate logistic regression test. Hospital charges and stays of these patients were assessed. The results showed that more hospital stages and charges are needed for patients in PF and CR-PF groups than in NOPF and NOCR-PF groups (P<0.05). The excessive drinking, soft remnant pancreas, preoperative albumin, and intraoperative blood transfusion are risk factors affecting both PF and CR-PF incidence. More professional surgeons can effectively reduce the PF and CR-PF incidence. Patients with PF and CR-PF need more hospital costs and stages than that in NOPF and NOCR-PF groups. It is critical that surgeons know the risk factors related to PF and CR-PF so as to take corresponding therapeutic regimens for each patient. |
| format | Article |
| id | doaj-art-a3f25baf55d44ec690972f1a3e933bde |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-a3f25baf55d44ec690972f1a3e933bde2025-02-03T05:58:51ZengWileyGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/917689917689Risk Factors and Medico-Economic Effect of Pancreatic Fistula after PancreaticoduodenectomyRenping Huang0Bing Liu1Hua Chen2Xuewei Bai3Rui Kong4Gang Wang5Yongwei Wang6Bei Sun7Yinghui Guan8Vascular Surgery, Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaVascular Surgery, Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaDepartment of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaDepartment of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaDepartment of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaDepartment of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaDepartment of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaDepartment of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaVascular Surgery, Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, ChinaThe study aimed to uncover the risk factors for the new defined pancreatic fistula (PF) and clinical related PF (CR-PF) after pancreaticoduodenectomy (PD) surgery and to evaluate the medico-economic effect of patients. A total of 412 patients were classified into two groups according to different criteria, PF and NOPF according to PF occurrence: CR-PF (grades B and C) and NOCR-PF (grade A) based on PF severity. A total of 28 factors were evaluated by univariate and multivariate logistic regression test. Hospital charges and stays of these patients were assessed. The results showed that more hospital stages and charges are needed for patients in PF and CR-PF groups than in NOPF and NOCR-PF groups (P<0.05). The excessive drinking, soft remnant pancreas, preoperative albumin, and intraoperative blood transfusion are risk factors affecting both PF and CR-PF incidence. More professional surgeons can effectively reduce the PF and CR-PF incidence. Patients with PF and CR-PF need more hospital costs and stages than that in NOPF and NOCR-PF groups. It is critical that surgeons know the risk factors related to PF and CR-PF so as to take corresponding therapeutic regimens for each patient.http://dx.doi.org/10.1155/2015/917689 |
| spellingShingle | Renping Huang Bing Liu Hua Chen Xuewei Bai Rui Kong Gang Wang Yongwei Wang Bei Sun Yinghui Guan Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy Gastroenterology Research and Practice |
| title | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
| title_full | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
| title_fullStr | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
| title_full_unstemmed | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
| title_short | Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy |
| title_sort | risk factors and medico economic effect of pancreatic fistula after pancreaticoduodenectomy |
| url | http://dx.doi.org/10.1155/2015/917689 |
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