Monostotic Fibrous Dysplasia of the Rib: A Case Report
Fibrous dysplasia is a noninherited bone disease in which abnormal differentiation of osteoblasts leads to replacement of normal marrow and cancellous bone by immature bone with fibrous stroma. Monostotic fibrous dysplasia accounts for 28% in the ribs. It is often asymptomatic and incidentally detec...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Case Reports in Orthopedics |
| Online Access: | http://dx.doi.org/10.1155/2012/690914 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559989152022528 |
|---|---|
| author | Asha Mahadevappa Sapna Patel Sunila Ravishankar Gubbanna V. Manjunath |
| author_facet | Asha Mahadevappa Sapna Patel Sunila Ravishankar Gubbanna V. Manjunath |
| author_sort | Asha Mahadevappa |
| collection | DOAJ |
| description | Fibrous dysplasia is a noninherited bone disease in which abnormal differentiation of osteoblasts leads to replacement of normal marrow and cancellous bone by immature bone with fibrous stroma. Monostotic fibrous dysplasia accounts for 28% in the ribs. It is often asymptomatic and incidentally detected on radiographs. As with many bone abnormalities, it can be superimposed by the formation of aneurysmal bone cysts. We report a case of a 70-year-old lady who presented with swelling on the chest wall of 20-ear duration and sudden increase in size for 8 months. Radiologically, X-ray and CT scan showed an expansible lesion of the medullary cavity with a ground-glass centre and thinning of cortex of the 5th rib. The resected lesion was a firm, well-defined solid, grey-white expansile mass replacing the medullary cavity. Histopathologically, benign fibrous spindle areas with disorganized irregular bony trabeculae were seen. Hemorrhagic spaces lined by osteoclast-like multinucleated giant cells were also noted. The diagnosis was fibrous dysplasia with aneurysmal bone cyst changes. Although fibrous dysplasia with aneurysmal bone cyst is rare, it should be taken into account in differential diagnosis of the rapidly growing solitary rib lesion. |
| format | Article |
| id | doaj-art-a3ef97dd85324ba7be72f9dba2becb78 |
| institution | Kabale University |
| issn | 2090-6749 2090-6757 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Orthopedics |
| spelling | doaj-art-a3ef97dd85324ba7be72f9dba2becb782025-02-03T01:28:49ZengWileyCase Reports in Orthopedics2090-67492090-67572012-01-01201210.1155/2012/690914690914Monostotic Fibrous Dysplasia of the Rib: A Case ReportAsha Mahadevappa0Sapna Patel1Sunila Ravishankar2Gubbanna V. Manjunath3Department of Pathology, JSS Medical College, JSS University, No. 1036, 5th Main 10th Cross, 1st Stage Vijayanagar, Karnataka, Mysore 570017, IndiaDepartment of Pathology, JSS Medical College, JSS University, No. 1036, 5th Main 10th Cross, 1st Stage Vijayanagar, Karnataka, Mysore 570017, IndiaDepartment of Pathology, JSS Medical College, JSS University, No. 1036, 5th Main 10th Cross, 1st Stage Vijayanagar, Karnataka, Mysore 570017, IndiaDepartment of Pathology, JSS Medical College, JSS University, No. 1036, 5th Main 10th Cross, 1st Stage Vijayanagar, Karnataka, Mysore 570017, IndiaFibrous dysplasia is a noninherited bone disease in which abnormal differentiation of osteoblasts leads to replacement of normal marrow and cancellous bone by immature bone with fibrous stroma. Monostotic fibrous dysplasia accounts for 28% in the ribs. It is often asymptomatic and incidentally detected on radiographs. As with many bone abnormalities, it can be superimposed by the formation of aneurysmal bone cysts. We report a case of a 70-year-old lady who presented with swelling on the chest wall of 20-ear duration and sudden increase in size for 8 months. Radiologically, X-ray and CT scan showed an expansible lesion of the medullary cavity with a ground-glass centre and thinning of cortex of the 5th rib. The resected lesion was a firm, well-defined solid, grey-white expansile mass replacing the medullary cavity. Histopathologically, benign fibrous spindle areas with disorganized irregular bony trabeculae were seen. Hemorrhagic spaces lined by osteoclast-like multinucleated giant cells were also noted. The diagnosis was fibrous dysplasia with aneurysmal bone cyst changes. Although fibrous dysplasia with aneurysmal bone cyst is rare, it should be taken into account in differential diagnosis of the rapidly growing solitary rib lesion.http://dx.doi.org/10.1155/2012/690914 |
| spellingShingle | Asha Mahadevappa Sapna Patel Sunila Ravishankar Gubbanna V. Manjunath Monostotic Fibrous Dysplasia of the Rib: A Case Report Case Reports in Orthopedics |
| title | Monostotic Fibrous Dysplasia of the Rib: A Case Report |
| title_full | Monostotic Fibrous Dysplasia of the Rib: A Case Report |
| title_fullStr | Monostotic Fibrous Dysplasia of the Rib: A Case Report |
| title_full_unstemmed | Monostotic Fibrous Dysplasia of the Rib: A Case Report |
| title_short | Monostotic Fibrous Dysplasia of the Rib: A Case Report |
| title_sort | monostotic fibrous dysplasia of the rib a case report |
| url | http://dx.doi.org/10.1155/2012/690914 |
| work_keys_str_mv | AT ashamahadevappa monostoticfibrousdysplasiaoftheribacasereport AT sapnapatel monostoticfibrousdysplasiaoftheribacasereport AT sunilaravishankar monostoticfibrousdysplasiaoftheribacasereport AT gubbannavmanjunath monostoticfibrousdysplasiaoftheribacasereport |