Constructing a fall risk prediction model for hospitalized patients using machine learning

Abstract Study objectives This study aimed to identify the risk factors associated with falls in hospitalized patients, develop a predictive risk model using machine learning algorithms, and evaluate the validity of the model’s predictions. Study design A cross-sectional design was employed using da...

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Main Authors: Cheng-Wei Kang, Zhao-Kui Yan, Jia-Liang Tian, Xiao-Bing Pu, Li-Xue Wu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-025-21284-8
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author Cheng-Wei Kang
Zhao-Kui Yan
Jia-Liang Tian
Xiao-Bing Pu
Li-Xue Wu
author_facet Cheng-Wei Kang
Zhao-Kui Yan
Jia-Liang Tian
Xiao-Bing Pu
Li-Xue Wu
author_sort Cheng-Wei Kang
collection DOAJ
description Abstract Study objectives This study aimed to identify the risk factors associated with falls in hospitalized patients, develop a predictive risk model using machine learning algorithms, and evaluate the validity of the model’s predictions. Study design A cross-sectional design was employed using data from the DRYAD public database. Research methods The study utilized data from the Fukushima Medical University Hospital Cohort Study, obtained from the DRYAD public database. 20% of the dataset was allocated as an independent test set, while the remaining 80% was utilized for training and validation. To address data imbalance in binary variables, the Synthetic Minority Oversampling Technique combined with Edited Nearest Neighbors (SMOTE-ENN) was applied. Univariate analysis and least absolute shrinkage and selection operator (LASSO) regression were used to analyze and screen variables. Predictive models were constructed by integrating key clinical features, and eight machine learning algorithms were evaluated to identify the most effective model. Additionally, SHAP (Shapley Additive Explanations) was used to interpret the predictive models and rank the importance of risk factors. Results The final model included the following variables: Adl_standing, Adl_evacuation, Age_group, Planned_surgery, Wheelchair, History_of_falls, Hypnotic_drugs, Psychotropic_drugs, and Remote_caring_system. Among the evaluated models, the Random Forest algorithm demonstrated superior performance, achieving an AUC of 0.814 (95% CI: 0.802–0.827) in the training set, 0.781 (95% CI: 0.740–0.821) in the validation set, and 0.795 (95% CI: 0.770–0.820) in the test set. Conclusion Machine learning algorithms, particularly Random Forest, are effective in predicting fall risk among hospitalized patients. These findings can significantly enhance fall prevention strategies within healthcare settings.
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spelling doaj-art-a3e60d5efec347edbda300b08addaafe2025-01-26T12:55:32ZengBMCBMC Public Health1471-24582025-01-0125111410.1186/s12889-025-21284-8Constructing a fall risk prediction model for hospitalized patients using machine learningCheng-Wei Kang0Zhao-Kui Yan1Jia-Liang Tian2Xiao-Bing Pu3Li-Xue Wu4Department of Orthopaedics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Orthopaedics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Orthopaedics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Orthopaedics, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Pathology, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityAbstract Study objectives This study aimed to identify the risk factors associated with falls in hospitalized patients, develop a predictive risk model using machine learning algorithms, and evaluate the validity of the model’s predictions. Study design A cross-sectional design was employed using data from the DRYAD public database. Research methods The study utilized data from the Fukushima Medical University Hospital Cohort Study, obtained from the DRYAD public database. 20% of the dataset was allocated as an independent test set, while the remaining 80% was utilized for training and validation. To address data imbalance in binary variables, the Synthetic Minority Oversampling Technique combined with Edited Nearest Neighbors (SMOTE-ENN) was applied. Univariate analysis and least absolute shrinkage and selection operator (LASSO) regression were used to analyze and screen variables. Predictive models were constructed by integrating key clinical features, and eight machine learning algorithms were evaluated to identify the most effective model. Additionally, SHAP (Shapley Additive Explanations) was used to interpret the predictive models and rank the importance of risk factors. Results The final model included the following variables: Adl_standing, Adl_evacuation, Age_group, Planned_surgery, Wheelchair, History_of_falls, Hypnotic_drugs, Psychotropic_drugs, and Remote_caring_system. Among the evaluated models, the Random Forest algorithm demonstrated superior performance, achieving an AUC of 0.814 (95% CI: 0.802–0.827) in the training set, 0.781 (95% CI: 0.740–0.821) in the validation set, and 0.795 (95% CI: 0.770–0.820) in the test set. Conclusion Machine learning algorithms, particularly Random Forest, are effective in predicting fall risk among hospitalized patients. These findings can significantly enhance fall prevention strategies within healthcare settings.https://doi.org/10.1186/s12889-025-21284-8Accidental fallsHospitalized patientsRisk factorsMachine learningPredictive modelingModel interpretation
spellingShingle Cheng-Wei Kang
Zhao-Kui Yan
Jia-Liang Tian
Xiao-Bing Pu
Li-Xue Wu
Constructing a fall risk prediction model for hospitalized patients using machine learning
BMC Public Health
Accidental falls
Hospitalized patients
Risk factors
Machine learning
Predictive modeling
Model interpretation
title Constructing a fall risk prediction model for hospitalized patients using machine learning
title_full Constructing a fall risk prediction model for hospitalized patients using machine learning
title_fullStr Constructing a fall risk prediction model for hospitalized patients using machine learning
title_full_unstemmed Constructing a fall risk prediction model for hospitalized patients using machine learning
title_short Constructing a fall risk prediction model for hospitalized patients using machine learning
title_sort constructing a fall risk prediction model for hospitalized patients using machine learning
topic Accidental falls
Hospitalized patients
Risk factors
Machine learning
Predictive modeling
Model interpretation
url https://doi.org/10.1186/s12889-025-21284-8
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