Monitoring of patients with hematological malignancies after anticancer therapy

The number of patients achieved continuous complete remission constantly increasing as a result of pediatric hematology development. Improvement and optimization of treatment protocols includes both efficacy increase and toxicity reduction, but today any type therapy is associated with risk of long-...

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Bibliographic Details
Main Authors: A. E. Rudneva, E. E. Ilyina
Format: Article
Language:Russian
Published: ABV-press 2015-01-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/131
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Summary:The number of patients achieved continuous complete remission constantly increasing as a result of pediatric hematology development. Improvement and optimization of treatment protocols includes both efficacy increase and toxicity reduction, but today any type therapy is associated with risk of long-term adverse effects.Children and adolescents who have received anticancer treatment – is a special cohort whose health requires a special observation. Thismonitoring program should be aimed at both remission control and early detection of possible treatment long-term side effects. Some side effects have long (five, ten or more years) latent period and observation of such patients should be carried out for a long time, respectively. This article provides a brief overview of international recommendations for monitoring children and adolescents after anticancer therapy, analyzed the situation with follow-up in Russia, and offers the variant of follow-up service organization in the clinic, based on the own experience. The article also considers issues about relapse and secondary tumors diagnosis. Using international recommendations the main side effects of chemo- and radiation therapy systematized. In conclusion, an example of a monitoring program designed for the individual patient, based on age, gender, previous disease and treatment is shown.
ISSN:1818-8346
2413-4023