BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA
Background: Gangrene is a severe complication of damaged tissue that can occur in people with Diabetes Mellitus (DM), putting them at risk for bacterial infection. A pus culture can show diabetic gangrene patients' infecting bacteria. Purpose: Determine the prevalence of infection-causing bacte...
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Universitas Airlangga
2024-03-01
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| Series: | Journal of Vocational Health Studies |
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| Online Access: | https://e-journal.unair.ac.id/JVHS/article/view/41535 |
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| author | Imro`atul Qona`ah Aliyah Siti Sundari Ratna Wahyuni Dwi Wahyu Indriati |
| author_facet | Imro`atul Qona`ah Aliyah Siti Sundari Ratna Wahyuni Dwi Wahyu Indriati |
| author_sort | Imro`atul Qona`ah |
| collection | DOAJ |
| description | Background: Gangrene is a severe complication of damaged tissue that can occur in people with Diabetes Mellitus (DM), putting them at risk for bacterial infection. A pus culture can show diabetic gangrene patients' infecting bacteria. Purpose: Determine the prevalence of infection-causing bacteria and antibiotic sensitivity tests in diabetic gangrene patients at Haji Regional General Hospital, East Java Province, for January-December 2021. Method: The method used in this study is observational analytical cross-sectional, which is based on secondary data and is analyzed using the percentage formula and Chi-Square test. Result: The data obtained from 39 patients revealed 29 (74.4%) positive patients for bacterial infection. The Gram-negative bacteria was found to cause infection more frequently (72.41%) than the Gram-positive bacteria (27.59%). The prevalence of Gram-negative bacteria species most frequently from Escherichia coli (ESBL) 13.79% (4/29), Klebsiella pneumoniae 10.35% (3/29), Proteus mirabilis 10.35% (3/29). While the dominant Gram-positive bacteria a Methicillin-Resistant Staphylococcus aureus (MRSA) 10.35% (3/29). The antibiotic sensitivity test showed that Gram-negative group were susceptible to ertapenem, meropenem, amikacin, gentamicin, and piperacillin tazobactam while resistant to ampicillin and cefazolin. The antibiotic sensitivity tests showed that the Gram-positive group was susceptible to linezolid, vancomycin, and tigecycline while resistant to tetracycline and ciprofloxacin. Conclusion: It is important to screen the bacterial profile causing gangrene and their antibiotic susceptibility pattern in DM patients in order to give proper treatment to DM patients. |
| format | Article |
| id | doaj-art-a3c00be2dd414c199ea86e072787637f |
| institution | Kabale University |
| issn | 2580-7161 2580-717X |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Journal of Vocational Health Studies |
| spelling | doaj-art-a3c00be2dd414c199ea86e072787637f2025-02-02T04:34:24ZengUniversitas AirlanggaJournal of Vocational Health Studies2580-71612580-717X2024-03-017315116010.20473/jvhs.V7.I3.2024.151-16039616BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYAImro`atul Qona`ah0Aliyah Siti Sundari1https://orcid.org/0000-0002-5655-9714Ratna Wahyuni2https://orcid.org/0000-0001-6791-1106Dwi Wahyu Indriati3https://orcid.org/0000-0003-4170-9094Department of Health, Faculty of Vocational Studies, Universitas Airlangga, IndonesiaDepartment of Health, Faculty of Vocational Studies, Universitas Airlangga, IndonesiaDepartment of Health, Faculty of Vocational Studies, Universitas Airlangga, Indonesia, Department of Health, Faculty of Vocational Studies, Universitas Airlangga, Indonesia, Background: Gangrene is a severe complication of damaged tissue that can occur in people with Diabetes Mellitus (DM), putting them at risk for bacterial infection. A pus culture can show diabetic gangrene patients' infecting bacteria. Purpose: Determine the prevalence of infection-causing bacteria and antibiotic sensitivity tests in diabetic gangrene patients at Haji Regional General Hospital, East Java Province, for January-December 2021. Method: The method used in this study is observational analytical cross-sectional, which is based on secondary data and is analyzed using the percentage formula and Chi-Square test. Result: The data obtained from 39 patients revealed 29 (74.4%) positive patients for bacterial infection. The Gram-negative bacteria was found to cause infection more frequently (72.41%) than the Gram-positive bacteria (27.59%). The prevalence of Gram-negative bacteria species most frequently from Escherichia coli (ESBL) 13.79% (4/29), Klebsiella pneumoniae 10.35% (3/29), Proteus mirabilis 10.35% (3/29). While the dominant Gram-positive bacteria a Methicillin-Resistant Staphylococcus aureus (MRSA) 10.35% (3/29). The antibiotic sensitivity test showed that Gram-negative group were susceptible to ertapenem, meropenem, amikacin, gentamicin, and piperacillin tazobactam while resistant to ampicillin and cefazolin. The antibiotic sensitivity tests showed that the Gram-positive group was susceptible to linezolid, vancomycin, and tigecycline while resistant to tetracycline and ciprofloxacin. Conclusion: It is important to screen the bacterial profile causing gangrene and their antibiotic susceptibility pattern in DM patients in order to give proper treatment to DM patients.https://e-journal.unair.ac.id/JVHS/article/view/41535antibiotic resistancediabetes melituse. coligangrenepus |
| spellingShingle | Imro`atul Qona`ah Aliyah Siti Sundari Ratna Wahyuni Dwi Wahyu Indriati BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA Journal of Vocational Health Studies antibiotic resistance diabetes melitus e. coli gangrene pus |
| title | BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA |
| title_full | BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA |
| title_fullStr | BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA |
| title_full_unstemmed | BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA |
| title_short | BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA |
| title_sort | bacterial profile and antibiotic susceptibility test among diabetes mellitus patients with gangrene in surabaya |
| topic | antibiotic resistance diabetes melitus e. coli gangrene pus |
| url | https://e-journal.unair.ac.id/JVHS/article/view/41535 |
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