The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital

Introduction: Coronavirus disease (COVID-19) is an infectious disease that increases pro-oxidant elements and decreases antioxidants. Vitamin C functions as a potent antioxidant in humans due to its electron-donating properties. This study aimed to explain the impact of three distinct vitamin C sup...

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Bibliographic Details
Main Authors: Yoga Akbar Arifandi, Alfian Nur Rosyid, Danti Nur Indiastuti, Wiwin Is Effendi
Format: Article
Language:English
Published: Fakultas Kedokteran Universitas Airlangga 2025-01-01
Series:Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
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Online Access:https://e-journal.unair.ac.id/JUXTA/article/view/60284
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Summary:Introduction: Coronavirus disease (COVID-19) is an infectious disease that increases pro-oxidant elements and decreases antioxidants. Vitamin C functions as a potent antioxidant in humans due to its electron-donating properties. This study aimed to explain the impact of three distinct vitamin C supplementation dosages in preventing disease severity progression among mild and moderate COVID-19 patients. Methods: This retrospective study used secondary data from 100 medical records (n=100). The subjects were classified into three categories based on the vitamin C dosage. The data were analyzed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26.0 for Windows. Results: Most of mild and moderate COVID-19 patients (78%) did not experience increased disease severity. Vitamin C supplementation significantly demonstrated a different outcome in preventing disease severity progression among the three groups (p=0.018). However, it did not significantly show any difference in reducing the duration of hospital stay (p=0.680). Conclusion: The impact of vitamin C supplementation on COVID-19 severity appeared to vary depending on the dosage administered. However, it did not affect the duration of the hospital stay.
ISSN:1907-3623
2684-9453