Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024: a study based on the AGREEⅡ

Objective To systematically assess the methodological quality of clinical practice guidelines for fungal diseases to provide a reference for the formulation of guidelines/consensuses in the field of fungal diseases in the future. Methods Guidelines and expert consensuses on fungal diseases were sear...

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Main Authors: Xiaopan WANG, Mengya SHANG, Wenjie FANG, Mingwei DU, Xinlin ZHU, Qi YIN, Xiaogang LIU, Weihua PAN, Yinuo LIU, Wanqing LIAO
Format: Article
Language:zho
Published: Editorial Office of Journal of Guangxi Medical University 2025-06-01
Series:Guangxi Yike Daxue xuebao
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Online Access:https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2025.03.021
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author Xiaopan WANG
Mengya SHANG
Wenjie FANG
Mingwei DU
Xinlin ZHU
Qi YIN
Xiaogang LIU
Weihua PAN
Yinuo LIU
Wanqing LIAO
author_facet Xiaopan WANG
Mengya SHANG
Wenjie FANG
Mingwei DU
Xinlin ZHU
Qi YIN
Xiaogang LIU
Weihua PAN
Yinuo LIU
Wanqing LIAO
author_sort Xiaopan WANG
collection DOAJ
description Objective To systematically assess the methodological quality of clinical practice guidelines for fungal diseases to provide a reference for the formulation of guidelines/consensuses in the field of fungal diseases in the future. Methods Guidelines and expert consensuses on fungal diseases were searched from relevant databases and related websites such as Medline (via PubMed), Embase, China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform, Chinese Biomedical Literature Database, China Clinical Guidelines Library Network, and China Medical Knowledge Base Guidelines Library from January 2023 to December 2024. After two researchers completed the consistency evaluation, the included guidelines and consensuses were evaluated for methodological quality and the results were analyzed using the Appraisal of Guidelines for Research & Evaluation (AGREE) instrumentⅡ, also known as AGREEⅡ. Results Twenty-two guidelines or consensuses were finally included, of which 8 were rated as grade A (recommended for adoption) and 14 were rated as grade B (recommendable after modification). The scoring rates of the six domains evaluated by AGREE Ⅱ were 8.21%±1.52% for Scope and Purpose, 65.53%±0.79% for Stakeholder Involvement, 68.94%±0.23% for Rigour of Development, 80.81%±0.45% for Clarity of Presentation, 6.35%±0.52% for Applicability, and 67.99% ±4.09% for Independence. Failure to document and disclose conflicts of interest among guideline development group members in terms of independence was a significant factor for score deduction.The guidelines/consensuses in 2024 were superior to those in 2023 in terms of rigour (P < 0.05). Conclusion The methodological quality of fungal disease guidelines and expert consensuses regarding participants, rigour, applicability, and independence needs to be further improved, and the guideline development needs to be in strict accordance with AGREEⅡ requirements to clarify conflicts of interest.
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spelling doaj-art-a3a53844db99426d868a5839b571865f2025-08-20T03:31:24ZzhoEditorial Office of Journal of Guangxi Medical UniversityGuangxi Yike Daxue xuebao1005-930X2025-06-0142347548210.16190/j.cnki.45-1211/r.2025.03.021gxykdxxb-42-3-475Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024: a study based on the AGREEⅡXiaopan WANG0Mengya SHANG1Wenjie FANG2Mingwei DU3Xinlin ZHU4Qi YIN5Xiaogang LIU6Weihua PAN7Yinuo LIU8Wanqing LIAO9Department of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Naval Medical University, Shanghai 200003, ChinaObjective To systematically assess the methodological quality of clinical practice guidelines for fungal diseases to provide a reference for the formulation of guidelines/consensuses in the field of fungal diseases in the future. Methods Guidelines and expert consensuses on fungal diseases were searched from relevant databases and related websites such as Medline (via PubMed), Embase, China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform, Chinese Biomedical Literature Database, China Clinical Guidelines Library Network, and China Medical Knowledge Base Guidelines Library from January 2023 to December 2024. After two researchers completed the consistency evaluation, the included guidelines and consensuses were evaluated for methodological quality and the results were analyzed using the Appraisal of Guidelines for Research & Evaluation (AGREE) instrumentⅡ, also known as AGREEⅡ. Results Twenty-two guidelines or consensuses were finally included, of which 8 were rated as grade A (recommended for adoption) and 14 were rated as grade B (recommendable after modification). The scoring rates of the six domains evaluated by AGREE Ⅱ were 8.21%±1.52% for Scope and Purpose, 65.53%±0.79% for Stakeholder Involvement, 68.94%±0.23% for Rigour of Development, 80.81%±0.45% for Clarity of Presentation, 6.35%±0.52% for Applicability, and 67.99% ±4.09% for Independence. Failure to document and disclose conflicts of interest among guideline development group members in terms of independence was a significant factor for score deduction.The guidelines/consensuses in 2024 were superior to those in 2023 in terms of rigour (P < 0.05). Conclusion The methodological quality of fungal disease guidelines and expert consensuses regarding participants, rigour, applicability, and independence needs to be further improved, and the guideline development needs to be in strict accordance with AGREEⅡ requirements to clarify conflicts of interest.https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2025.03.021fungal diseasesclinical practice guidelinesexpert consensusesthe appraisal of guidelines for research & evaluation instrumentⅱmethodological quality assessment
spellingShingle Xiaopan WANG
Mengya SHANG
Wenjie FANG
Mingwei DU
Xinlin ZHU
Qi YIN
Xiaogang LIU
Weihua PAN
Yinuo LIU
Wanqing LIAO
Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024: a study based on the AGREEⅡ
Guangxi Yike Daxue xuebao
fungal diseases
clinical practice guidelines
expert consensuses
the appraisal of guidelines for research & evaluation instrumentⅱ
methodological quality assessment
title Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024: a study based on the AGREEⅡ
title_full Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024: a study based on the AGREEⅡ
title_fullStr Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024: a study based on the AGREEⅡ
title_full_unstemmed Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024: a study based on the AGREEⅡ
title_short Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024: a study based on the AGREEⅡ
title_sort quality assessment of clinical practice guidelines and consensuses for fungal diseases in china from 2023 to 2024 a study based on the agreeii
topic fungal diseases
clinical practice guidelines
expert consensuses
the appraisal of guidelines for research & evaluation instrumentⅱ
methodological quality assessment
url https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2025.03.021
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