Effect of discontinuing antipsychotic medications on the risk of hospitalization in long-term care: a machine learning-based analysis

Effect of discontinuing antipsychotic medications on the risk of hospitalization in long-term care: a machine learning-based analysis

Abstract Background Antipsychotic medications are frequently prescribed to older residents of long-term care facilities (LTCFs) despite their limited efficacy and considerable safety risks. While discontinuation of these drugs might help reduce their associated morbidity, the impact of stopping anti...

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Main Authors: Mikko Nuutinen, Riikka-Leena Leskelä, Daniela Fialova, Ira Haavisto, Harriet Finne-Soveri, Jokke Häsä, Johanna Edgren, Hein van Hout, Daniel E. da Cunha Leme, John P. Hirdes, Graziano Onder, Rosa Liperoti
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Medicine
Subjects:
Antipsychotic medications
Long-term care
Machine learning
Online Access:https://doi.org/10.1186/s12916-025-04304-7
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