Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility
Herb-induced liver injury (HILI) is often an underreported sequela for many herbal remedies due to the lack of safety measurements involving these supplements. Cimicifuga racemosa and Thuja occidentalis are two herbal medications commonly used by women for fertility purposes. Many herbal preparation...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/8858310 |
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| author | Rohan Patel Fareeha Alavi Susel Ortega Ajsza Matela |
| author_facet | Rohan Patel Fareeha Alavi Susel Ortega Ajsza Matela |
| author_sort | Rohan Patel |
| collection | DOAJ |
| description | Herb-induced liver injury (HILI) is often an underreported sequela for many herbal remedies due to the lack of safety measurements involving these supplements. Cimicifuga racemosa and Thuja occidentalis are two herbal medications commonly used by women for fertility purposes. Many herbal preparations of these two supplements do not specify the risks behind their individual usage. We present a case of a 40-year-old woman who developed acute liver injury after concomitant use of these two products assessed for causality using the updated RUCAM. Upon a detailed investigation, the patient did not have evidence of underlying liver disease or any other risk factors to explain her presentation. After discontinuation of both herbal supplements, the patient had complete resolution of her symptoms and a significant improvement of transaminitis. This report highlights the importance of potential risk of hepatotoxicity induced by concomitant use of Cimicifuga racemosa and Thuja occidentalis. |
| format | Article |
| id | doaj-art-a3893a0386204ea79c32eaebb9493c50 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-a3893a0386204ea79c32eaebb9493c502025-02-03T00:58:46ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362021-01-01202110.1155/2021/88583108858310Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for FertilityRohan Patel0Fareeha Alavi1Susel Ortega2Ajsza Matela3American University of the Caribbean, School of Medicine, 880 SW 145th Avenue, Suite 202, Pembroke Pines, FL 33027, USADepartment of Internal Medicine, BronxCare Health System, 1650 Grand Concourse, Bronx, NY 10457, USADepartment of Internal Medicine, BronxCare Health System, 1650 Grand Concourse, Bronx, NY 10457, USADivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, BronxCare Health System, 1650 Grand Concourse, Bronx, NY 10457, USAHerb-induced liver injury (HILI) is often an underreported sequela for many herbal remedies due to the lack of safety measurements involving these supplements. Cimicifuga racemosa and Thuja occidentalis are two herbal medications commonly used by women for fertility purposes. Many herbal preparations of these two supplements do not specify the risks behind their individual usage. We present a case of a 40-year-old woman who developed acute liver injury after concomitant use of these two products assessed for causality using the updated RUCAM. Upon a detailed investigation, the patient did not have evidence of underlying liver disease or any other risk factors to explain her presentation. After discontinuation of both herbal supplements, the patient had complete resolution of her symptoms and a significant improvement of transaminitis. This report highlights the importance of potential risk of hepatotoxicity induced by concomitant use of Cimicifuga racemosa and Thuja occidentalis.http://dx.doi.org/10.1155/2021/8858310 |
| spellingShingle | Rohan Patel Fareeha Alavi Susel Ortega Ajsza Matela Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility Case Reports in Gastrointestinal Medicine |
| title | Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility |
| title_full | Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility |
| title_fullStr | Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility |
| title_full_unstemmed | Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility |
| title_short | Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility |
| title_sort | herb induced liver injury by cimicifuga racemosa and thuja occidentalis herbal medications for fertility |
| url | http://dx.doi.org/10.1155/2021/8858310 |
| work_keys_str_mv | AT rohanpatel herbinducedliverinjurybycimicifugaracemosaandthujaoccidentalisherbalmedicationsforfertility AT fareehaalavi herbinducedliverinjurybycimicifugaracemosaandthujaoccidentalisherbalmedicationsforfertility AT suselortega herbinducedliverinjurybycimicifugaracemosaandthujaoccidentalisherbalmedicationsforfertility AT ajszamatela herbinducedliverinjurybycimicifugaracemosaandthujaoccidentalisherbalmedicationsforfertility |