Elucidating molecular lipid perturbations in trigeminal neuralgia using cerebrospinal fluid lipidomics

Elucidating molecular lipid perturbations in trigeminal neuralgia using cerebrospinal fluid lipidomics

Abstract Trigeminal neuralgia (TN) is a neuropathic facial pain disorder characterized by severe stabbing pain along the trigeminal nerve. While its pathogenesis remains unclear, nerve demyelination and inflammation are likely involved. Current research has primarily focused on various blood-based o...

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Bibliographic Details
Main Authors: Dongyuan Xu, Xuan Dai, Qianwen He, Zhimin Mei, Yixuan Zhou, Jingwei Zhao, Nanxiang Xiong
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Trigeminal neuralgia
Cerebrospinal fluid
Lipidomics
Mass spectrometry
Neuroinflammation
Demyelination
Online Access:https://doi.org/10.1038/s41598-025-89755-x
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https://doi.org/10.1038/s41598-025-89755-x

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