Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors
Falls can be considered a disabling feature in Parkinson’s disease. We aimed to identify risk factors for falling, testing simultaneously the ability of disease-specific and balance-related measures. We evaluated 171 patients, collecting demographic and clinical data, including standardized assessme...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2014/432924 |
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| author | Lorena R. S. Almeida Guilherme T. Valença Nádja N. Negreiros Elen B. Pinto Jamary Oliveira-Filho |
| author_facet | Lorena R. S. Almeida Guilherme T. Valença Nádja N. Negreiros Elen B. Pinto Jamary Oliveira-Filho |
| author_sort | Lorena R. S. Almeida |
| collection | DOAJ |
| description | Falls can be considered a disabling feature in Parkinson’s disease. We aimed to identify risk factors for falling, testing simultaneously the ability of disease-specific and balance-related measures. We evaluated 171 patients, collecting demographic and clinical data, including standardized assessments with the Unified Parkinson’s Disease Rating Scale (UPDRS), activities of daily living (ADL) and motor sections, modified Hoehn and Yahr Scale, Schwab and England, eight-item Parkinson’s Disease Questionnaire, Activities-specific Balance Confidence Scale, Falls Efficacy Scale-International (FES-I), Berg Balance Scale, Dynamic Gait Index, Functional Reach, and Timed Up and Go. ROC curves were constructed to determine the cutoff scores for all measures. Variables with P<0.1 entered a logistic regression model. The prevalence of recurrent falls was 30% (95% CI 24%–38%). In multivariate analysis, independent risk factors for recurrent falls were (P<0.05) levodopa equivalent dose (OR = 1.283 per 100 mg increase; 95% CI = 1.092–1.507), UPDRS-ADL > 16 points (OR = 10.0; 95% CI = 3.6–28.3), FES-I > 30 points (OR = 6.0; 95% CI = 1.6–22.6), and Berg ≤ 48 points (OR = 3.9; 95% CI = 1.2–12.7).We encourage the utilization of these modifiable risk factors in the screening of fall risk. |
| format | Article |
| id | doaj-art-a35fa4ea61684fb687422657974c56a6 |
| institution | Kabale University |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-a35fa4ea61684fb687422657974c56a62025-02-03T05:44:02ZengWileyParkinson's Disease2090-80832042-00802014-01-01201410.1155/2014/432924432924Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk FactorsLorena R. S. Almeida0Guilherme T. Valença1Nádja N. Negreiros2Elen B. Pinto3Jamary Oliveira-Filho4Movement Disorders Clinic, Bahia State Health Attention Center for the Elderly, Avenida ACM, s/n, Ed. José Maria de Magalhães Netto, Iguatemi, 41820-000 Salvador, BA, BrazilMovement Disorders Clinic, Bahia State Health Attention Center for the Elderly, Avenida ACM, s/n, Ed. José Maria de Magalhães Netto, Iguatemi, 41820-000 Salvador, BA, BrazilMovement Disorders Clinic, Bahia State Health Attention Center for the Elderly, Avenida ACM, s/n, Ed. José Maria de Magalhães Netto, Iguatemi, 41820-000 Salvador, BA, BrazilPost-Graduate Program in Health Sciences, Federal University of Bahia, Largo do Terreiro de Jesus, s/n, Centro Histórico, 40025-010 Salvador, BA, BrazilPost-Graduate Program in Health Sciences, Federal University of Bahia, Largo do Terreiro de Jesus, s/n, Centro Histórico, 40025-010 Salvador, BA, BrazilFalls can be considered a disabling feature in Parkinson’s disease. We aimed to identify risk factors for falling, testing simultaneously the ability of disease-specific and balance-related measures. We evaluated 171 patients, collecting demographic and clinical data, including standardized assessments with the Unified Parkinson’s Disease Rating Scale (UPDRS), activities of daily living (ADL) and motor sections, modified Hoehn and Yahr Scale, Schwab and England, eight-item Parkinson’s Disease Questionnaire, Activities-specific Balance Confidence Scale, Falls Efficacy Scale-International (FES-I), Berg Balance Scale, Dynamic Gait Index, Functional Reach, and Timed Up and Go. ROC curves were constructed to determine the cutoff scores for all measures. Variables with P<0.1 entered a logistic regression model. The prevalence of recurrent falls was 30% (95% CI 24%–38%). In multivariate analysis, independent risk factors for recurrent falls were (P<0.05) levodopa equivalent dose (OR = 1.283 per 100 mg increase; 95% CI = 1.092–1.507), UPDRS-ADL > 16 points (OR = 10.0; 95% CI = 3.6–28.3), FES-I > 30 points (OR = 6.0; 95% CI = 1.6–22.6), and Berg ≤ 48 points (OR = 3.9; 95% CI = 1.2–12.7).We encourage the utilization of these modifiable risk factors in the screening of fall risk.http://dx.doi.org/10.1155/2014/432924 |
| spellingShingle | Lorena R. S. Almeida Guilherme T. Valença Nádja N. Negreiros Elen B. Pinto Jamary Oliveira-Filho Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors Parkinson's Disease |
| title | Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors |
| title_full | Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors |
| title_fullStr | Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors |
| title_full_unstemmed | Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors |
| title_short | Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors |
| title_sort | recurrent falls in people with parkinson s disease without cognitive impairment focusing on modifiable risk factors |
| url | http://dx.doi.org/10.1155/2014/432924 |
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