Suprasellar Ganglioglioma: Expanding the Differential Diagnosis

This case study describes a young man with symptoms suggestive of the presence of a space-occupying lesion within the cranial cavity. Imaging studies confirmed a lesion in the suprasellar region and surgical intervention to remove the tumor yielded an unexpected diagnosis. Neuroimaging characteristi...

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Main Authors: Isabella Tondi Resta, Arminder Singh, Bruce C. Gilbert, Mumtaz V. Rojiani, Cargill Alleyne, Amyn M. Rojiani
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2018/9486064
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author Isabella Tondi Resta
Arminder Singh
Bruce C. Gilbert
Mumtaz V. Rojiani
Cargill Alleyne
Amyn M. Rojiani
author_facet Isabella Tondi Resta
Arminder Singh
Bruce C. Gilbert
Mumtaz V. Rojiani
Cargill Alleyne
Amyn M. Rojiani
author_sort Isabella Tondi Resta
collection DOAJ
description This case study describes a young man with symptoms suggestive of the presence of a space-occupying lesion within the cranial cavity. Imaging studies confirmed a lesion in the suprasellar region and surgical intervention to remove the tumor yielded an unexpected diagnosis. Neuroimaging characteristics and histopathology including immunohistochemistry are described. Gangliogliomas are uncommon CNS neoplasms and are most commonly found in the temporal and frontal lobes of young, male adults. They are rarely seen in the suprasellar region and only a handful of cases have been reported to date. The differential diagnoses associated with these suprasellar region lesions can be dependent on the age of the patient and neuroimaging characteristics. The present report highlights the importance of histopathological examination and the need to consider a wide range of diagnostic entities in the differential diagnosis of lesions in this topographic distribution, including rarely encountered tumors such as gangliogliomas.
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language English
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series Case Reports in Pathology
spelling doaj-art-a34f12ffcd5d40ae8e7ae07c7f4de2e12025-02-03T01:29:09ZengWileyCase Reports in Pathology2090-67812090-679X2018-01-01201810.1155/2018/94860649486064Suprasellar Ganglioglioma: Expanding the Differential DiagnosisIsabella Tondi Resta0Arminder Singh1Bruce C. Gilbert2Mumtaz V. Rojiani3Cargill Alleyne4Amyn M. Rojiani5Department of Pathology, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USADepartment of Neurology, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USADepartment of Radiology, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USADepartment of Pathology, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USADepartment of Neurosurgery, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USADepartment of Pathology, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USAThis case study describes a young man with symptoms suggestive of the presence of a space-occupying lesion within the cranial cavity. Imaging studies confirmed a lesion in the suprasellar region and surgical intervention to remove the tumor yielded an unexpected diagnosis. Neuroimaging characteristics and histopathology including immunohistochemistry are described. Gangliogliomas are uncommon CNS neoplasms and are most commonly found in the temporal and frontal lobes of young, male adults. They are rarely seen in the suprasellar region and only a handful of cases have been reported to date. The differential diagnoses associated with these suprasellar region lesions can be dependent on the age of the patient and neuroimaging characteristics. The present report highlights the importance of histopathological examination and the need to consider a wide range of diagnostic entities in the differential diagnosis of lesions in this topographic distribution, including rarely encountered tumors such as gangliogliomas.http://dx.doi.org/10.1155/2018/9486064
spellingShingle Isabella Tondi Resta
Arminder Singh
Bruce C. Gilbert
Mumtaz V. Rojiani
Cargill Alleyne
Amyn M. Rojiani
Suprasellar Ganglioglioma: Expanding the Differential Diagnosis
Case Reports in Pathology
title Suprasellar Ganglioglioma: Expanding the Differential Diagnosis
title_full Suprasellar Ganglioglioma: Expanding the Differential Diagnosis
title_fullStr Suprasellar Ganglioglioma: Expanding the Differential Diagnosis
title_full_unstemmed Suprasellar Ganglioglioma: Expanding the Differential Diagnosis
title_short Suprasellar Ganglioglioma: Expanding the Differential Diagnosis
title_sort suprasellar ganglioglioma expanding the differential diagnosis
url http://dx.doi.org/10.1155/2018/9486064
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