Repeated CMV Infection in a Heart Transplantation Patient
Infections are one of the leading causes of morbidity and mortality in heart transplantation (HTx). Cytomegalovirus (CMV) is the most common viral infection during the first year after HTx, but it is more unusual after this time. We present the case of a patient who underwent an HTx due to a severe...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2012/305920 |
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| _version_ | 1832556081742610432 |
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| author | Josep Melero-Ferrer Ignacio J. Sanchez-Lazaro Amparo Navea-Tejerina Luis Almenar-Bonet Marino Blanes-Julia Luis Martinez-Dolz Antonio Salvador-Sanz |
| author_facet | Josep Melero-Ferrer Ignacio J. Sanchez-Lazaro Amparo Navea-Tejerina Luis Almenar-Bonet Marino Blanes-Julia Luis Martinez-Dolz Antonio Salvador-Sanz |
| author_sort | Josep Melero-Ferrer |
| collection | DOAJ |
| description | Infections are one of the leading causes of morbidity and mortality in heart transplantation (HTx). Cytomegalovirus (CMV) is the most common viral infection during the first year after HTx, but it is more unusual after this time. We present the case of a patient who underwent an HTx due to a severe ischemic heart disease. Although the patient did not have a high risk for CMV, infection, he suffered a reactivation during the first year and then up to six more episodes, especially in his eyes. The patient received different treatments against CMV and the immunosuppression was changed several times. Finally, everolimus was introduced instead of cyclosporine, and mycophenolate mofetil was withdrawn. The presented case provides an example of how the immunosupresion plays a key role in some infections in spite of being a suitable antiviral treatment. |
| format | Article |
| id | doaj-art-a30ae6ff71b6431e83b06f8bdd60ce25 |
| institution | Kabale University |
| issn | 2090-6943 2090-6951 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Transplantation |
| spelling | doaj-art-a30ae6ff71b6431e83b06f8bdd60ce252025-02-03T05:46:29ZengWileyCase Reports in Transplantation2090-69432090-69512012-01-01201210.1155/2012/305920305920Repeated CMV Infection in a Heart Transplantation PatientJosep Melero-Ferrer0Ignacio J. Sanchez-Lazaro1Amparo Navea-Tejerina2Luis Almenar-Bonet3Marino Blanes-Julia4Luis Martinez-Dolz5Antonio Salvador-Sanz6Unidad de Insuficiencia Cardíaca y Trasplante Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainUnidad de Insuficiencia Cardíaca y Trasplante Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainFundaciónn Oftalmológica del Mediterráneo, 46015 Valencia, SpainUnidad de Insuficiencia Cardíaca y Trasplante Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainUnidad de Enfermedades Infeciosas, Servicio de Medicina Interna, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainUnidad de Insuficiencia Cardíaca y Trasplante Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainUnidad de Insuficiencia Cardíaca y Trasplante Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainInfections are one of the leading causes of morbidity and mortality in heart transplantation (HTx). Cytomegalovirus (CMV) is the most common viral infection during the first year after HTx, but it is more unusual after this time. We present the case of a patient who underwent an HTx due to a severe ischemic heart disease. Although the patient did not have a high risk for CMV, infection, he suffered a reactivation during the first year and then up to six more episodes, especially in his eyes. The patient received different treatments against CMV and the immunosuppression was changed several times. Finally, everolimus was introduced instead of cyclosporine, and mycophenolate mofetil was withdrawn. The presented case provides an example of how the immunosupresion plays a key role in some infections in spite of being a suitable antiviral treatment.http://dx.doi.org/10.1155/2012/305920 |
| spellingShingle | Josep Melero-Ferrer Ignacio J. Sanchez-Lazaro Amparo Navea-Tejerina Luis Almenar-Bonet Marino Blanes-Julia Luis Martinez-Dolz Antonio Salvador-Sanz Repeated CMV Infection in a Heart Transplantation Patient Case Reports in Transplantation |
| title | Repeated CMV Infection in a Heart Transplantation Patient |
| title_full | Repeated CMV Infection in a Heart Transplantation Patient |
| title_fullStr | Repeated CMV Infection in a Heart Transplantation Patient |
| title_full_unstemmed | Repeated CMV Infection in a Heart Transplantation Patient |
| title_short | Repeated CMV Infection in a Heart Transplantation Patient |
| title_sort | repeated cmv infection in a heart transplantation patient |
| url | http://dx.doi.org/10.1155/2012/305920 |
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