The role of feedback in the formation of morphogen territories
In this paper, we consider a mathematical model for the forma-tion of spatial morphogen territories of two key morphogens: Wingless (Wg)and Decapentaplegic (DPP), involved in leg development of Drosophila. Wedefine a gene regulatory network (GRN) that utilizes autoactivation and cross-inhibition (mo...
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Main Authors: | David Iron, Adeela Syed, Heidi Theisen, Tamas Lukacsovich, Mehrangiz Naghibi, Lawrence J. Marsh, Frederic Y. M. Wan, Qing Nie |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2008-02-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.277 |
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