The role of feedback in the formation of morphogen territories

In this paper, we consider a mathematical model for the forma-tion of spatial morphogen territories of two key morphogens: Wingless (Wg)and Decapentaplegic (DPP), involved in leg development of Drosophila. Wedefine a gene regulatory network (GRN) that utilizes autoactivation and cross-inhibition (mo...

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Bibliographic Details
Main Authors: David Iron, Adeela Syed, Heidi Theisen, Tamas Lukacsovich, Mehrangiz Naghibi, Lawrence J. Marsh, Frederic Y. M. Wan, Qing Nie
Format: Article
Language:English
Published: AIMS Press 2008-02-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.277
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