An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI
Mammary Paget’s disease is a rare presentation of breast cancer. At clinical examination, it is characterized by skin lesions of the nipple-areola complex, almost always a sign of malignancy. In fact, it is often associated with an underlying mammary ductal carcinoma in situ (DCIS) or invasive carci...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/2013/206235 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832545459613204480 |
|---|---|
| author | Eleonora Gaspari Aurora Ricci Valeria Liberto Angela Lia Scarano Maria Fornari Giovanni Simonetti |
| author_facet | Eleonora Gaspari Aurora Ricci Valeria Liberto Angela Lia Scarano Maria Fornari Giovanni Simonetti |
| author_sort | Eleonora Gaspari |
| collection | DOAJ |
| description | Mammary Paget’s disease is a rare presentation of breast cancer. At clinical examination, it is characterized by skin lesions of the nipple-areola complex, almost always a sign of malignancy. In fact, it is often associated with an underlying mammary ductal carcinoma in situ (DCIS) or invasive carcinoma. An underlying carcinoma is also common in women with negative mammography and ultrasound (US); in these cases, magnetic resonance imaging (MRI) is a diagnostic tool useful in the detection of occult cancer. We described an unusual case of mammary Paget’s disease with underlying DCIS, in a patient without nipple-areola complex alterations and/or palpable lump. On suspicion of Paget’s disease, the patient underwent MRI examination that proved useful for an accurate diagnosis. Biopsy confirmed dynamic MRI findings. |
| format | Article |
| id | doaj-art-a2e8af8f6a35435e8d4e5fecbfdba9bd |
| institution | Kabale University |
| issn | 2090-6862 2090-6870 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-a2e8af8f6a35435e8d4e5fecbfdba9bd2025-02-03T07:25:45ZengWileyCase Reports in Radiology2090-68622090-68702013-01-01201310.1155/2013/206235206235An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRIEleonora Gaspari0Aurora Ricci1Valeria Liberto2Angela Lia Scarano3Maria Fornari4Giovanni Simonetti5Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyMammary Paget’s disease is a rare presentation of breast cancer. At clinical examination, it is characterized by skin lesions of the nipple-areola complex, almost always a sign of malignancy. In fact, it is often associated with an underlying mammary ductal carcinoma in situ (DCIS) or invasive carcinoma. An underlying carcinoma is also common in women with negative mammography and ultrasound (US); in these cases, magnetic resonance imaging (MRI) is a diagnostic tool useful in the detection of occult cancer. We described an unusual case of mammary Paget’s disease with underlying DCIS, in a patient without nipple-areola complex alterations and/or palpable lump. On suspicion of Paget’s disease, the patient underwent MRI examination that proved useful for an accurate diagnosis. Biopsy confirmed dynamic MRI findings.http://dx.doi.org/10.1155/2013/206235 |
| spellingShingle | Eleonora Gaspari Aurora Ricci Valeria Liberto Angela Lia Scarano Maria Fornari Giovanni Simonetti An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI Case Reports in Radiology |
| title | An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI |
| title_full | An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI |
| title_fullStr | An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI |
| title_full_unstemmed | An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI |
| title_short | An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI |
| title_sort | unusual case of mammary paget s disease diagnosed using dynamic contrast enhanced mri |
| url | http://dx.doi.org/10.1155/2013/206235 |
| work_keys_str_mv | AT eleonoragaspari anunusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT auroraricci anunusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT valerialiberto anunusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT angelaliascarano anunusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT mariafornari anunusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT giovannisimonetti anunusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT eleonoragaspari unusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT auroraricci unusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT valerialiberto unusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT angelaliascarano unusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT mariafornari unusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri AT giovannisimonetti unusualcaseofmammarypagetsdiseasediagnosedusingdynamiccontrastenhancedmri |