Computational design of binding proteins to EGFR domain II.

Computational design of binding proteins to EGFR domain II.

We developed a process to produce novel interactions between two previously unrelated proteins. This process selects protein scaffolds and designs protein interfaces that bind to a surface patch of interest on a target protein. Scaffolds with shapes complementary to the target surface patch were scr...

Full description

Saved in:
Bibliographic Details
Main Authors: Yoon Sup Choi, Soomin Yoon, Kyung-Lock Kim, Jiho Yoo, Parkyong Song, Minsoo Kim, Young-Eun Shin, Won Jun Yang, Jung-eun Noh, Hyun-Soo Cho, Sanguk Kim, Junho Chung, Sung Ho Ryu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0092513&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items