Comparative study between homeopathy and nimesulide on the prevention of bone resorption in experimental periodontitis in rats

Periodontitis is a chronic disease characterized by bone loss and inflammatory changes. We studied the effect of a homeopathic agent (Mercúrios Corrosivos 6 CH) and a non-steroidal anti-inflammatory drug (nimesulide) on the alveolar bone loss progression in experimentally induced periodontitis in ra...

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Main Authors: Thais Marchini Oliveira, Bruna Centurion, Mariana Gigliotti, Tiago Mergulhão, Vivien Sakai, Thiago Dionísio, Flávio Faria, Gustavo Pompermaier Garlet, Carlos Ferreira dos Santos
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul. Faculdade de Odontologia 2010-10-01
Series:Revista da Faculdade de Odontologia de Porto Alegre
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Online Access:https://seer.ufrgs.br/index.php/educacaoerealidade;www.scielo.br/index.php/RevistadaFaculdadeOdontologia/article/view/18165
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Summary:Periodontitis is a chronic disease characterized by bone loss and inflammatory changes. We studied the effect of a homeopathic agent (Mercúrios Corrosivos 6 CH) and a non-steroidal anti-inflammatory drug (nimesulide) on the alveolar bone loss progression in experimentally induced periodontitis in rats. Sixty (60) Wistar rats were separated into group 1 (homeopathy), group 2 (nimesulide) and group 3 (saline solution). Silk ligatures were placed at the gingival margin level of the lower right first molar of all rats. Alveolar bone loss was evaluated by light microscopic analysis and analyzed using software Image J. The results were submitted to the analysis of variance (ANOVA) and Tukey’s posttest (p
ISSN:0566-1854
2177-0018