The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper

Methicillin-resistant Staphylococcus aureus (MRSA) is being seen with greater frequency in most hospitals and other health care facilities across Canada. The organism may cause life-threatening infections and has been associated with institutional outbreaks. Several studies have confirmed that MRSA...

Full description

Saved in:
Bibliographic Details
Main Authors: Andrew E Simor, Mark Loeb, the CIDS/CAMM Guidelines Committee
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2004/531434
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832567815940341760
author Andrew E Simor
Mark Loeb
the CIDS/CAMM Guidelines Committee
author_facet Andrew E Simor
Mark Loeb
the CIDS/CAMM Guidelines Committee
author_sort Andrew E Simor
collection DOAJ
description Methicillin-resistant Staphylococcus aureus (MRSA) is being seen with greater frequency in most hospitals and other health care facilities across Canada. The organism may cause life-threatening infections and has been associated with institutional outbreaks. Several studies have confirmed that MRSA infection is associated with increased morbidity and mortality compared with infections caused by susceptible strains, even when the presence of comorbidities is accounted for. Treatment of MRSA infection is complicated by the fact that these organisms are resistant to multiple antimicrobial agents, so treatment options are limited. The effectiveness of decolonization therapy (attempting to eradicate MRSA carriage) is also uncertain. This paper reviews the medical management of MRSA infections, discusses the potential role of decolonization and provides an overview of evidence to support recommended infection control practices.
format Article
id doaj-art-a2ca0e0b270541fbba2dadce29c5d376
institution Kabale University
issn 1180-2332
language English
publishDate 2004-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases
spelling doaj-art-a2ca0e0b270541fbba2dadce29c5d3762025-02-03T01:00:35ZengWileyCanadian Journal of Infectious Diseases1180-23322004-01-01151394810.1155/2004/531434The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position PaperAndrew E Simor0Mark Loeb1the CIDS/CAMM Guidelines CommitteeDepartments of Medicine and Microbiology, Sunnybrook and Women’s College Health Sciences Centre, Toronto, Ontario, CanadaHamilton Regional Laboratory Program, Hamilton, Ontario, CanadaMethicillin-resistant Staphylococcus aureus (MRSA) is being seen with greater frequency in most hospitals and other health care facilities across Canada. The organism may cause life-threatening infections and has been associated with institutional outbreaks. Several studies have confirmed that MRSA infection is associated with increased morbidity and mortality compared with infections caused by susceptible strains, even when the presence of comorbidities is accounted for. Treatment of MRSA infection is complicated by the fact that these organisms are resistant to multiple antimicrobial agents, so treatment options are limited. The effectiveness of decolonization therapy (attempting to eradicate MRSA carriage) is also uncertain. This paper reviews the medical management of MRSA infections, discusses the potential role of decolonization and provides an overview of evidence to support recommended infection control practices.http://dx.doi.org/10.1155/2004/531434
spellingShingle Andrew E Simor
Mark Loeb
the CIDS/CAMM Guidelines Committee
The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper
Canadian Journal of Infectious Diseases
title The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper
title_full The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper
title_fullStr The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper
title_full_unstemmed The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper
title_short The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper
title_sort management of infection and colonization due to methicillin resistant staphylococcus aureus a cids camm position paper
url http://dx.doi.org/10.1155/2004/531434
work_keys_str_mv AT andrewesimor themanagementofinfectionandcolonizationduetomethicillinresistantstaphylococcusaureusacidscammpositionpaper
AT markloeb themanagementofinfectionandcolonizationduetomethicillinresistantstaphylococcusaureusacidscammpositionpaper
AT thecidscammguidelinescommittee themanagementofinfectionandcolonizationduetomethicillinresistantstaphylococcusaureusacidscammpositionpaper
AT andrewesimor managementofinfectionandcolonizationduetomethicillinresistantstaphylococcusaureusacidscammpositionpaper
AT markloeb managementofinfectionandcolonizationduetomethicillinresistantstaphylococcusaureusacidscammpositionpaper
AT thecidscammguidelinescommittee managementofinfectionandcolonizationduetomethicillinresistantstaphylococcusaureusacidscammpositionpaper