The Calprotectin Fragment, CPa9-HNE, Is a Plasma Biomarker of Mild Chronic Obstructive Pulmonary Disease

The Calprotectin Fragment, CPa9-HNE, Is a Plasma Biomarker of Mild Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease predominantly of the small airways and parenchyma. COPD lungs exhibit an influx of circulating innate immune cells, which, when isolated, display impaired functions, including imbalanced protease secretion. In addition to...

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Bibliographic Details
Main Authors: Mugdha M. Joglekar, Jannie M. B. Sand, Theo Borghuis, Diana J. Leeming, Morten Karsdal, Frank Klont, Russell P. Bowler, Barbro N. Melgert, Janette K. Burgess, Simon D. Pouwels
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
COPD
biomarkers
ECM fragments
CPa9-HNE
S100A9
DAMPs
Online Access:https://www.mdpi.com/2073-4409/14/15/1155
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