LncRNA‐Mediated TPI1 and PKM2 Promote Self‐Renewal and Chemoresistance in GBM

LncRNA‐Mediated TPI1 and PKM2 Promote Self‐Renewal and Chemoresistance in GBM

Abstract Temozolomide (TMZ) resistance is one of the major reasons for poor prognosis in patients with glioblastoma (GBM). Long noncoding RNAs (lncRNAs) are involved in multiple biological processes, including TMZ resistance. Linc00942 is a potential regulator of TMZ sensitivity in GBM cells is show...

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Main Authors: Changxiao Yang, Ziwei Li, Kaifu Tian, Xiangqi Meng, Xinyu Wang, Dan Song, Xuan Wang, Tianye Xu, Penggang Sun, Junzhe Zhong, Yu Song, Wenbin Ma, Yuxiang Liu, Daohan Yu, Ruofei Shen, Chuanlu Jiang, Jinquan Cai
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
GBM
Linc00942
PKM2
TPI1
TMZ resistance
Online Access:https://doi.org/10.1002/advs.202402600
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