Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia

We report a case of M. pneumoniae infection presenting with severe hemolytic anemia in a 4-year-old girl, with a ten-day history of paleness, weakness, and nonproductive cough. She was very pale and tachycardic. However, she was not tachypneic. Chest examination showed normal breath sounds. No rhonc...

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Main Authors: Zafer Kurugol, Serife Sebnem Onen, Guldane Koturoglu
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/649850
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author Zafer Kurugol
Serife Sebnem Onen
Guldane Koturoglu
author_facet Zafer Kurugol
Serife Sebnem Onen
Guldane Koturoglu
author_sort Zafer Kurugol
collection DOAJ
description We report a case of M. pneumoniae infection presenting with severe hemolytic anemia in a 4-year-old girl, with a ten-day history of paleness, weakness, and nonproductive cough. She was very pale and tachycardic. However, she was not tachypneic. Chest examination showed normal breath sounds. No rhoncus or whistling was heard. As the erythrocyte sedimentation rate was excessively elevated, the differential diagnosis primarily comprised hematological malignancies. Direct Coombs' test was positive. Diagnosis of M. pneumoniae infection was confirmed by elevated levels of M. pneumoniae IgG and IgM antibodies and a chest X-ray suggestive of atypical pneumonia. The patient was treated with clarithromycin and packed red cell transfusion and showed a favorable recovery within ten days after admission. In conclusion, this case demonstrates that severe hemolytic anemia caused by M. pneumoniae is not always associated with severe pulmonary involvement, even when the respiratory infection is very mild, M. pneumoniae may be the cause of severe anemia.
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series Case Reports in Medicine
spelling doaj-art-a283460906df4674b2d7c78789c45ef92025-02-03T01:03:46ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/649850649850Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumoniaZafer Kurugol0Serife Sebnem Onen1Guldane Koturoglu2Department of pediatrics, Ege University Faculty of Medicine, Izmir, 35100 Bornova, TurkeyDepartment of pediatrics, Ege University Faculty of Medicine, Izmir, 35100 Bornova, TurkeyDepartment of pediatrics, Ege University Faculty of Medicine, Izmir, 35100 Bornova, TurkeyWe report a case of M. pneumoniae infection presenting with severe hemolytic anemia in a 4-year-old girl, with a ten-day history of paleness, weakness, and nonproductive cough. She was very pale and tachycardic. However, she was not tachypneic. Chest examination showed normal breath sounds. No rhoncus or whistling was heard. As the erythrocyte sedimentation rate was excessively elevated, the differential diagnosis primarily comprised hematological malignancies. Direct Coombs' test was positive. Diagnosis of M. pneumoniae infection was confirmed by elevated levels of M. pneumoniae IgG and IgM antibodies and a chest X-ray suggestive of atypical pneumonia. The patient was treated with clarithromycin and packed red cell transfusion and showed a favorable recovery within ten days after admission. In conclusion, this case demonstrates that severe hemolytic anemia caused by M. pneumoniae is not always associated with severe pulmonary involvement, even when the respiratory infection is very mild, M. pneumoniae may be the cause of severe anemia.http://dx.doi.org/10.1155/2012/649850
spellingShingle Zafer Kurugol
Serife Sebnem Onen
Guldane Koturoglu
Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia
Case Reports in Medicine
title Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia
title_full Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia
title_fullStr Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia
title_full_unstemmed Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia
title_short Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia
title_sort severe hemolytic anemia associated with mild pneumonia caused by mycoplasma pneumonia
url http://dx.doi.org/10.1155/2012/649850
work_keys_str_mv AT zaferkurugol severehemolyticanemiaassociatedwithmildpneumoniacausedbymycoplasmapneumonia
AT serifesebnemonen severehemolyticanemiaassociatedwithmildpneumoniacausedbymycoplasmapneumonia
AT guldanekoturoglu severehemolyticanemiaassociatedwithmildpneumoniacausedbymycoplasmapneumonia