Danhong injection alleviates OGD-induced blood-brain barrier injury via VEGFR2/PI3K/AKT pathway based on network pharmacology and experimental evidence

Danhong injection alleviates OGD-induced blood-brain barrier injury via VEGFR2/PI3K/AKT pathway based on network pharmacology and experimental evidence

Objective: Previous studies have shown that Danhong injection (DHI) has a protective effect on the blood-brain barrier (BBB) function after ischemic stroke. However, the role of DHI in protecting the integrity of the BBB after ischemic stroke through endothelial cells is still unclear. The purpose o...

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Bibliographic Details
Main Authors: Yutong Zhang, Meixia Xie, Jiayin Liang, Li Li, Shumei Wang, Minghua Xian
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Journal of Holistic Integrative Pharmacy
Subjects:
Danhong injection
Cerebral ischemic stroke
Network pharmacology
VEGFR2/PI3K/AKT pathway
Blood-brain-barrier
Online Access:http://www.sciencedirect.com/science/article/pii/S2707368824000165
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