Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease

Musculoskeletal manifestations are the most common extraintestinal manifestations in inflammatory bowel diseases. Some appendicular manifestations are independent of gut inflammation and are treated with standard anti-inflammatory strategies. On the other hand, axial involvement is linked to gut inf...

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Main Authors: Tejas Sheth, C. S. Pitchumoni, Kiron M. Das
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2015/387891
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author Tejas Sheth
C. S. Pitchumoni
Kiron M. Das
author_facet Tejas Sheth
C. S. Pitchumoni
Kiron M. Das
author_sort Tejas Sheth
collection DOAJ
description Musculoskeletal manifestations are the most common extraintestinal manifestations in inflammatory bowel diseases. Some appendicular manifestations are independent of gut inflammation and are treated with standard anti-inflammatory strategies. On the other hand, axial involvement is linked to gut inflammatory activity; hence, there is a considerable amount of treatment overlap. Biological therapies have revolutionized management of inflammatory bowel diseases as well as of associated articular manifestations. Newer mechanisms driving gut associated arthropathy have surfaced in the past decade and have enhanced our interests in novel treatment targets. Introduction of biosimilar molecules is expected in the US market in the near future and will provide an opportunity for considerable cost savings on healthcare. A multidisciplinary approach involving a gastroenterologist, rheumatologist, and physical therapist is ideal for these patients.
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series Gastroenterology Research and Practice
spelling doaj-art-a24eafb470bb413abd36da0bfd8c78862025-02-03T01:09:23ZengWileyGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/387891387891Management of Musculoskeletal Manifestations in Inflammatory Bowel DiseaseTejas Sheth0C. S. Pitchumoni1Kiron M. Das2Department of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USADepartment of Gastroenterology, Rutgers-St. Peter’s University Hospital, New Brunswick, NJ, USADivision of Gastroenterology and Hepatology, Crohn’s and Colitis Center of NJ, Rutgers-Robert Wood Johnson Medical School, Clinical Academic Building, 125 Paterson Street, Suite 5100B, New Brunswick, NJ 08901-1962, USAMusculoskeletal manifestations are the most common extraintestinal manifestations in inflammatory bowel diseases. Some appendicular manifestations are independent of gut inflammation and are treated with standard anti-inflammatory strategies. On the other hand, axial involvement is linked to gut inflammatory activity; hence, there is a considerable amount of treatment overlap. Biological therapies have revolutionized management of inflammatory bowel diseases as well as of associated articular manifestations. Newer mechanisms driving gut associated arthropathy have surfaced in the past decade and have enhanced our interests in novel treatment targets. Introduction of biosimilar molecules is expected in the US market in the near future and will provide an opportunity for considerable cost savings on healthcare. A multidisciplinary approach involving a gastroenterologist, rheumatologist, and physical therapist is ideal for these patients.http://dx.doi.org/10.1155/2015/387891
spellingShingle Tejas Sheth
C. S. Pitchumoni
Kiron M. Das
Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease
Gastroenterology Research and Practice
title Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease
title_full Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease
title_fullStr Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease
title_full_unstemmed Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease
title_short Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease
title_sort management of musculoskeletal manifestations in inflammatory bowel disease
url http://dx.doi.org/10.1155/2015/387891
work_keys_str_mv AT tejassheth managementofmusculoskeletalmanifestationsininflammatoryboweldisease
AT cspitchumoni managementofmusculoskeletalmanifestationsininflammatoryboweldisease
AT kironmdas managementofmusculoskeletalmanifestationsininflammatoryboweldisease