Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease
Musculoskeletal manifestations are the most common extraintestinal manifestations in inflammatory bowel diseases. Some appendicular manifestations are independent of gut inflammation and are treated with standard anti-inflammatory strategies. On the other hand, axial involvement is linked to gut inf...
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Format: | Article |
Language: | English |
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Wiley
2015-01-01
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Series: | Gastroenterology Research and Practice |
Online Access: | http://dx.doi.org/10.1155/2015/387891 |
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author | Tejas Sheth C. S. Pitchumoni Kiron M. Das |
author_facet | Tejas Sheth C. S. Pitchumoni Kiron M. Das |
author_sort | Tejas Sheth |
collection | DOAJ |
description | Musculoskeletal manifestations are the most common extraintestinal manifestations in inflammatory bowel diseases. Some appendicular manifestations are independent of gut inflammation and are treated with standard anti-inflammatory strategies. On the other hand, axial involvement is linked to gut inflammatory activity; hence, there is a considerable amount of treatment overlap. Biological therapies have revolutionized management of inflammatory bowel diseases as well as of associated articular manifestations. Newer mechanisms driving gut associated arthropathy have surfaced in the past decade and have enhanced our interests in novel treatment targets. Introduction of biosimilar molecules is expected in the US market in the near future and will provide an opportunity for considerable cost savings on healthcare. A multidisciplinary approach involving a gastroenterologist, rheumatologist, and physical therapist is ideal for these patients. |
format | Article |
id | doaj-art-a24eafb470bb413abd36da0bfd8c7886 |
institution | Kabale University |
issn | 1687-6121 1687-630X |
language | English |
publishDate | 2015-01-01 |
publisher | Wiley |
record_format | Article |
series | Gastroenterology Research and Practice |
spelling | doaj-art-a24eafb470bb413abd36da0bfd8c78862025-02-03T01:09:23ZengWileyGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/387891387891Management of Musculoskeletal Manifestations in Inflammatory Bowel DiseaseTejas Sheth0C. S. Pitchumoni1Kiron M. Das2Department of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USADepartment of Gastroenterology, Rutgers-St. Peter’s University Hospital, New Brunswick, NJ, USADivision of Gastroenterology and Hepatology, Crohn’s and Colitis Center of NJ, Rutgers-Robert Wood Johnson Medical School, Clinical Academic Building, 125 Paterson Street, Suite 5100B, New Brunswick, NJ 08901-1962, USAMusculoskeletal manifestations are the most common extraintestinal manifestations in inflammatory bowel diseases. Some appendicular manifestations are independent of gut inflammation and are treated with standard anti-inflammatory strategies. On the other hand, axial involvement is linked to gut inflammatory activity; hence, there is a considerable amount of treatment overlap. Biological therapies have revolutionized management of inflammatory bowel diseases as well as of associated articular manifestations. Newer mechanisms driving gut associated arthropathy have surfaced in the past decade and have enhanced our interests in novel treatment targets. Introduction of biosimilar molecules is expected in the US market in the near future and will provide an opportunity for considerable cost savings on healthcare. A multidisciplinary approach involving a gastroenterologist, rheumatologist, and physical therapist is ideal for these patients.http://dx.doi.org/10.1155/2015/387891 |
spellingShingle | Tejas Sheth C. S. Pitchumoni Kiron M. Das Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease Gastroenterology Research and Practice |
title | Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease |
title_full | Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease |
title_fullStr | Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease |
title_full_unstemmed | Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease |
title_short | Management of Musculoskeletal Manifestations in Inflammatory Bowel Disease |
title_sort | management of musculoskeletal manifestations in inflammatory bowel disease |
url | http://dx.doi.org/10.1155/2015/387891 |
work_keys_str_mv | AT tejassheth managementofmusculoskeletalmanifestationsininflammatoryboweldisease AT cspitchumoni managementofmusculoskeletalmanifestationsininflammatoryboweldisease AT kironmdas managementofmusculoskeletalmanifestationsininflammatoryboweldisease |