The TP53 Arg72Pro polymorphism predicts visual and neurodegenerative outcomes in retinal detachment

The TP53 Arg72Pro polymorphism predicts visual and neurodegenerative outcomes in retinal detachment

Abstract Retinal detachment (RD) separates the retina from the retinal epithelium, causing photoreceptor apoptosis and irreversible vision loss. Even with successful surgical reattachment, complete visual recovery is not guaranteed. The TP53 Arg72Pro polymorphism, implicated in apoptosis, has emerge...

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Main Authors: Nadia Galindo-Cabello, Eva M. Sobas-Abad, Rebeca Lapresa, Jesús Agulla, Ángeles Almeida, Antonio López, José Carlos Pastor, Salvador Pastor-Idoate, Ricardo Usategui-Martín
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07739-1
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