Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery

Background. Roux-en-Y gastric bypass (RYGBP) is an established method for treatment of obesity, a condition of chronic inflammation with liver steatosis, characterised by increased erythrocyte sedimentation rate (ESR), white blood cell count (WBC), liver enzymes, and decreased magnesium (Mg). We inv...

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Main Authors: Hans-Erik Johansson, Arvo Haenni, Björn Zethelius
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2011/273105
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author Hans-Erik Johansson
Arvo Haenni
Björn Zethelius
author_facet Hans-Erik Johansson
Arvo Haenni
Björn Zethelius
author_sort Hans-Erik Johansson
collection DOAJ
description Background. Roux-en-Y gastric bypass (RYGBP) is an established method for treatment of obesity, a condition of chronic inflammation with liver steatosis, characterised by increased erythrocyte sedimentation rate (ESR), white blood cell count (WBC), liver enzymes, and decreased magnesium (Mg). We investigated alterations, if any, in ESR, WBC, alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), and Mg after RYGBP. Methods. 21 morbidly obese nondiabetic patients who underwent RYGBP surgery were evaluated preoperatively (baseline), then 1 year (1st followup) and 3.5 years (2nd followup) after RYGBP and compared to an untreated control group. Results. Body mass index, ESR, WBC, ALT, and GGT were all significantly reduced at 1 year in the RYGBP group (30%, 35%, 20%, 45%, and 57%, resp.) while Mg increased by 6%, compared to control group (P=0.001−0.009). Conclusions. Obese patients treated by RYGBP show sustained reductions in ESR, WBC, ALT, and GGT possibly due to reduced liver steatosis and increased Mg.
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spelling doaj-art-a234eacd195c489991dbb05b38660c322025-02-03T01:24:29ZengWileyJournal of Obesity2090-07082090-07162011-01-01201110.1155/2011/273105273105Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass SurgeryHans-Erik Johansson0Arvo Haenni1Björn Zethelius2Department of Public Health and Caring Sciences/Geriatrics, Uppsala University Hospital, 75185 Uppsala, SwedenDepartment of Public Health and Caring Sciences/Geriatrics, Uppsala University Hospital, 75185 Uppsala, SwedenDepartment of Public Health and Caring Sciences/Geriatrics, Uppsala University Hospital, 75185 Uppsala, SwedenBackground. Roux-en-Y gastric bypass (RYGBP) is an established method for treatment of obesity, a condition of chronic inflammation with liver steatosis, characterised by increased erythrocyte sedimentation rate (ESR), white blood cell count (WBC), liver enzymes, and decreased magnesium (Mg). We investigated alterations, if any, in ESR, WBC, alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), and Mg after RYGBP. Methods. 21 morbidly obese nondiabetic patients who underwent RYGBP surgery were evaluated preoperatively (baseline), then 1 year (1st followup) and 3.5 years (2nd followup) after RYGBP and compared to an untreated control group. Results. Body mass index, ESR, WBC, ALT, and GGT were all significantly reduced at 1 year in the RYGBP group (30%, 35%, 20%, 45%, and 57%, resp.) while Mg increased by 6%, compared to control group (P=0.001−0.009). Conclusions. Obese patients treated by RYGBP show sustained reductions in ESR, WBC, ALT, and GGT possibly due to reduced liver steatosis and increased Mg.http://dx.doi.org/10.1155/2011/273105
spellingShingle Hans-Erik Johansson
Arvo Haenni
Björn Zethelius
Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery
Journal of Obesity
title Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery
title_full Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery
title_fullStr Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery
title_full_unstemmed Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery
title_short Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery
title_sort changes in erythrocyte sedimentation rate white blood cell count liver enzymes and magnesium after gastric bypass surgery
url http://dx.doi.org/10.1155/2011/273105
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