Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water
Abstract A new humic acid-based nanomagnetic copper(II) composite was prepared and used as an eco-friendly recoverable catalyst for synthesizing 1,4-disubstituted 1,2,3-triazoles. The synthesis was done via the three-component click reaction of alkyl halide, sodium azide, and terminal alkyne with go...
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Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-87392-y |
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| author | Beheshteh Arjmandzadeh Abbas Ali Jafari |
| author_facet | Beheshteh Arjmandzadeh Abbas Ali Jafari |
| author_sort | Beheshteh Arjmandzadeh |
| collection | DOAJ |
| description | Abstract A new humic acid-based nanomagnetic copper(II) composite was prepared and used as an eco-friendly recoverable catalyst for synthesizing 1,4-disubstituted 1,2,3-triazoles. The synthesis was done via the three-component click reaction of alkyl halide, sodium azide, and terminal alkyne with good to excellent yield. A simple magnetic copper acetate composite, Fe3O4@HA-Cu(OAc)2, was prepared using humic acid and characterized by SEM, TEM, XRD, EDX, EDS-mapping, VSM, TGA, AAS, and FT-IR. The catalyst showed high catalytic potential in a one-pot three-component click reaction in the synthesis of 1,2,3-triazoles. The nanomagnetic Fe3O4@HA-Cu(OAc)2 catalyst demonstrated high efficiency, stability, compatibility with oxygen/water and recyclable copper(II), with cost-effectiveness. The catalyst was easily recovered with an external magnetic field, and therefore, time and energy were saved as no filtration or decantation technique was needed. Due to the high dispersibility in water, nanomagnetic Fe3O4@HA-Cu(OAc)2 was utilized as a highly efficient catalyst for the click synthesis of triazoles. |
| format | Article |
| id | doaj-art-a22f8f69a5b3450ea9f4b88ebe16b0ca |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-a22f8f69a5b3450ea9f4b88ebe16b0ca2025-02-02T12:21:18ZengNature PortfolioScientific Reports2045-23222025-01-0115111410.1038/s41598-025-87392-yFe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in waterBeheshteh Arjmandzadeh0Abbas Ali Jafari1Department of Chemistry, Yazd UniversityDepartment of Chemistry, Yazd UniversityAbstract A new humic acid-based nanomagnetic copper(II) composite was prepared and used as an eco-friendly recoverable catalyst for synthesizing 1,4-disubstituted 1,2,3-triazoles. The synthesis was done via the three-component click reaction of alkyl halide, sodium azide, and terminal alkyne with good to excellent yield. A simple magnetic copper acetate composite, Fe3O4@HA-Cu(OAc)2, was prepared using humic acid and characterized by SEM, TEM, XRD, EDX, EDS-mapping, VSM, TGA, AAS, and FT-IR. The catalyst showed high catalytic potential in a one-pot three-component click reaction in the synthesis of 1,2,3-triazoles. The nanomagnetic Fe3O4@HA-Cu(OAc)2 catalyst demonstrated high efficiency, stability, compatibility with oxygen/water and recyclable copper(II), with cost-effectiveness. The catalyst was easily recovered with an external magnetic field, and therefore, time and energy were saved as no filtration or decantation technique was needed. Due to the high dispersibility in water, nanomagnetic Fe3O4@HA-Cu(OAc)2 was utilized as a highly efficient catalyst for the click synthesis of triazoles.https://doi.org/10.1038/s41598-025-87392-y |
| spellingShingle | Beheshteh Arjmandzadeh Abbas Ali Jafari Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water Scientific Reports |
| title | Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water |
| title_full | Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water |
| title_fullStr | Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water |
| title_full_unstemmed | Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water |
| title_short | Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water |
| title_sort | fe3o4 ha cu oac 2 nanocomposite as a nanomagnetic water compatible catalyst for efficient synthesis of 1 2 3 triazoles in water |
| url | https://doi.org/10.1038/s41598-025-87392-y |
| work_keys_str_mv | AT beheshteharjmandzadeh fe3o4hacuoac2nanocompositeasananomagneticwatercompatiblecatalystforefficientsynthesisof123triazolesinwater AT abbasalijafari fe3o4hacuoac2nanocompositeasananomagneticwatercompatiblecatalystforefficientsynthesisof123triazolesinwater |