Germinal center dynamics during acute and chronic infection
The ability of the immune system to clear pathogens is limited during chronic virus infections where potent long-lived plasma and memory B-cells are produced only after germinal center B-cells undergo many rounds of somatic hypermutations. In this paper, we investigate the mechanisms of germinal cen...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2017-05-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2017037 |
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