Inflammation and autophagy in peripheral nerves of rodent models with metabolic syndrome and type 2 diabetes mellitus

Inflammation and autophagy in peripheral nerves of rodent models with metabolic syndrome and type 2 diabetes mellitus

Metabolic syndrome (MetS) and type 2 diabetes mellitus (T2D) are associated with inflammation and the accumulation of macrophages in peripheral nerves, which increases the risk of developing peripheral neuropathy (PN). We have previously investigated that macrophage infiltration in the peripheral ne...

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Main Authors: Petra Baum, Thomas Ebert, Nora Klöting, Sontje Krupka, Matthias König, Sabine Paeschke, Peggy Stock, Michal Bulc, Matthias Blüher, Katarzyna Palus, Marcin Nowicki, Joanna Kosacka
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Neuroscience Research
Subjects:
Inflammation
Autophagy
Metabolic syndrome
T2D
PDN
ob/ob mice
Online Access:http://www.sciencedirect.com/science/article/pii/S0168010225000707
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