Leveraging chorionic villus biopsies for the derivation of patient-specific trophoblast stem cells

Leveraging chorionic villus biopsies for the derivation of patient-specific trophoblast stem cells

Abstract Human trophoblast stem (TS) cells are informative in vitro models for the generation and testing of biologically meaningful hypotheses. The goal of this project was to derive patient-specific TS cell lines from clinically available chorionic villus biopsies. Cell outgrowths were captured fr...

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Main Authors: Kaela M. Varberg, Ayelen Moreno-Irusta, Allynson Novoa, Brynne Musser, Joseph M. Varberg, Jeremy P. Goering, Irfan Saadi, Khursheed Iqbal, Hiroaki Okae, Takahiro Arima, John Williams, Margareta D. Pisarska, Michael J. Soares
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08393-1
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https://doi.org/10.1038/s42003-025-08393-1

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