Development and validation of a logistic regression model for the diagnosis of colorectal cancer

Development and validation of a logistic regression model for the diagnosis of colorectal cancer

Abstract Colorectal cancer (CRC) diagnosis is challenging due to generalized symptoms. Various biomarker models exist, but their clinical application is limited by low sensitivity and heterogeneous cutoff values. This study aimed to develop and validate a diagnostic model for CRC. Data from 489 pati...

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Bibliographic Details
Main Authors: Cong Li, Weili Zhang, Qichen Chen, Fei Xiao, Xia Yang, Binyi Xiao, Yanshuang Cheng, Jiayi Qin, Xueying Li, Desen Wan, Zhizhong Pan, Jianhong Peng, Xiaojun Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Colorectal cancer
Logistic regression
Serum biomarkers
Early diagnosis
AUC
Online Access:https://doi.org/10.1038/s41598-025-98968-z
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