MiR-506 suppresses proliferation, migration, and invasion of melanoma cells by modulating EMT and DNA damage homologous recombination repair pathway

MiR-506 suppresses proliferation, migration, and invasion of melanoma cells by modulating EMT and DNA damage homologous recombination repair pathway

[Objective] To investigate the biological function of miR-506 in malignant melanoma and its regulatory mechanism on mesenchymal epithelial transition (MET) and DNA damage homologous recombination repair pathway. [Methods] The expression of miR-506 in 48 cases of fresh malignant melanoma tissues was...

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Bibliographic Details
Main Authors: LI Ting, XIANG Lijie, FU Laihua, HAO Mengze, LIU Xinyue, YANG Jilong
Format: Article
Language:zho
Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology 2025-07-01
Series:Pifu-xingbing zhenliaoxue zazhi
Subjects:
malignant melanoma
mir-506
mesenchymal epithelial transformation
dna damage homologous recombination repair
Online Access:http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.07.002
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