Spatiotemporal and genomic analysis of carbapenem resistance elements in Enterobacterales from hospital inpatients and natural water ecosystems of an Irish city

Spatiotemporal and genomic analysis of carbapenem resistance elements in Enterobacterales from hospital inpatients and natural water ecosystems of an Irish city

ABSTRACT Carbapenemase-producing Enterobacterales (CPE) is a diverse group of often multidrug-resistant organisms. Surveillance and control of infections are complicated due to the inter-species spread of carbapenemase-encoding genes (CEGs) on mobile genetic elements (MGEs), including plasmids and t...

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Main Authors: Mark Maguire, Carlos Serna, Natalia Montero Serra, Aneta Kovarova, Louise O’Connor, Niamh Cahill, Brigid Hooban, Niall DeLappe, Wendy Brennan, Genevieve Devane, Martin Cormican, Dearbháile Morris, Simone C. Coughlan, Georgios Miliotis, Bruno Gonzalez-Zorn, Liam P. Burke
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:Microbiology Spectrum
Subjects:
antibiotic resistance
plasmids
transposons
Enterobacterales
carbapenems
environmental microbiology
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00904-24
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