Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency
In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. Because life-threatening disseminated BCG disease may occur in children with primary immunodeficiency, vaccination strategy against...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/527569 |
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| _version_ | 1832558051799859200 |
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| author | Sílvia Bacalhau Cristina Freitas Rosalina Valente Deolinda Barata Conceição Neves Katrin Schäfer Annelie Lubatschofski Ansgar Schulz João Farela Neves |
| author_facet | Sílvia Bacalhau Cristina Freitas Rosalina Valente Deolinda Barata Conceição Neves Katrin Schäfer Annelie Lubatschofski Ansgar Schulz João Farela Neves |
| author_sort | Sílvia Bacalhau |
| collection | DOAJ |
| description | In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. Because life-threatening disseminated BCG disease may occur in children with primary immunodeficiency, vaccination strategy against tuberculosis should be redefined in non-high-burden countries. We report the case of a patient with X-linked severe combined immunodeficiency (SCID) who developed disseminated BCG disease, highlighting the specific strategies adopted. |
| format | Article |
| id | doaj-art-a1b97a51656f44c78649f75bd9fcbe8a |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-a1b97a51656f44c78649f75bd9fcbe8a2025-02-03T01:33:21ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/527569527569Successful Handling of Disseminated BCG Disease in a Child with Severe Combined ImmunodeficiencySílvia Bacalhau0Cristina Freitas1Rosalina Valente2Deolinda Barata3Conceição Neves4Katrin Schäfer5Annelie Lubatschofski6Ansgar Schulz7João Farela Neves8Pediatric Intensive Care Unit, Hospital Dona Estefânia, 1169-045 Lisboa, PortugalPediatric Intensive Care Unit, Hospital Dona Estefânia, 1169-045 Lisboa, PortugalPediatric Intensive Care Unit, Hospital Dona Estefânia, 1169-045 Lisboa, PortugalPediatric Intensive Care Unit, Hospital Dona Estefânia, 1169-045 Lisboa, PortugalInfectology Unit, Hospital Dona Estefânia, Rua Jacinta Marto, 1169-045 Lisboa, PortugalDepartment of Immunology, Rheumatology and Stem Cell Transplantation, University Children's Hospital, 89073-89081 Ulm, GermanyDepartment of Immunology, Rheumatology and Stem Cell Transplantation, University Children's Hospital, 89073-89081 Ulm, GermanyDepartment of Immunology, Rheumatology and Stem Cell Transplantation, University Children's Hospital, 89073-89081 Ulm, GermanyInfectology Unit, Hospital Dona Estefânia, Rua Jacinta Marto, 1169-045 Lisboa, PortugalIn high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. Because life-threatening disseminated BCG disease may occur in children with primary immunodeficiency, vaccination strategy against tuberculosis should be redefined in non-high-burden countries. We report the case of a patient with X-linked severe combined immunodeficiency (SCID) who developed disseminated BCG disease, highlighting the specific strategies adopted.http://dx.doi.org/10.1155/2011/527569 |
| spellingShingle | Sílvia Bacalhau Cristina Freitas Rosalina Valente Deolinda Barata Conceição Neves Katrin Schäfer Annelie Lubatschofski Ansgar Schulz João Farela Neves Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency Case Reports in Medicine |
| title | Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency |
| title_full | Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency |
| title_fullStr | Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency |
| title_full_unstemmed | Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency |
| title_short | Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency |
| title_sort | successful handling of disseminated bcg disease in a child with severe combined immunodeficiency |
| url | http://dx.doi.org/10.1155/2011/527569 |
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