The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years
Objective. Few studies have suggested an inverse relation between coffee intake and serum concentrations of uric acid (UA), but none has addressed the relation in men and women separately. We examined the relation between coffee intake and serum UA levels in free-living middle-aged and elderly men a...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2010/930757 |
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| author | Ngoc Minh Pham Daigo Yoshida Makiko Morita Guang Yin Kengo Toyomura Keizo Ohnaka Ryoichi Takayanagi Suminori Kono |
| author_facet | Ngoc Minh Pham Daigo Yoshida Makiko Morita Guang Yin Kengo Toyomura Keizo Ohnaka Ryoichi Takayanagi Suminori Kono |
| author_sort | Ngoc Minh Pham |
| collection | DOAJ |
| description | Objective. Few studies have suggested an inverse relation between coffee intake and serum concentrations of uric acid (UA), but none has addressed the relation in men and women separately. We examined the relation between coffee intake and serum UA levels in free-living middle-aged and elderly men and women in Fukuoka, Japan. Methods. Study subjects were derived from the baseline survey of a cohort study on lifestyle-related diseases, and included 11.662 men and women aged 49–76 years; excluded were those with medication for gout and hyperuricemia, use of diuretic drugs, and medical care for cancer or chronic kidney disease. Statistical adjustment was made for body mass index, alcohol use, hypertension, diabetes mellitus, and other factors. Results. There were inverse associations of coffee consumption with serum UA concentrations and hyperuricemia in men regardless of adjustment for covariates. Women showed a statistically significant, but weaker, inverse association between coffee and serum UA levels after allowance for the confounding factors. Conclusion. The findings add to evidence for a protective association between coffee intake and hyperuricemia. |
| format | Article |
| id | doaj-art-a1b41d7df5864055818976a2e8a1eb96 |
| institution | Kabale University |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-a1b41d7df5864055818976a2e8a1eb962025-02-03T05:50:43ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322010-01-01201010.1155/2010/930757930757The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 YearsNgoc Minh Pham0Daigo Yoshida1Makiko Morita2Guang Yin3Kengo Toyomura4Keizo Ohnaka5Ryoichi Takayanagi6Suminori Kono7Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, JapanDepartment of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, JapanDepartment of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, JapanDepartment of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, JapanDepartment of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, JapanDepartment of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, JapanDepartment of Medicine and Bio-Regulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, JapanDepartment of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, JapanObjective. Few studies have suggested an inverse relation between coffee intake and serum concentrations of uric acid (UA), but none has addressed the relation in men and women separately. We examined the relation between coffee intake and serum UA levels in free-living middle-aged and elderly men and women in Fukuoka, Japan. Methods. Study subjects were derived from the baseline survey of a cohort study on lifestyle-related diseases, and included 11.662 men and women aged 49–76 years; excluded were those with medication for gout and hyperuricemia, use of diuretic drugs, and medical care for cancer or chronic kidney disease. Statistical adjustment was made for body mass index, alcohol use, hypertension, diabetes mellitus, and other factors. Results. There were inverse associations of coffee consumption with serum UA concentrations and hyperuricemia in men regardless of adjustment for covariates. Women showed a statistically significant, but weaker, inverse association between coffee and serum UA levels after allowance for the confounding factors. Conclusion. The findings add to evidence for a protective association between coffee intake and hyperuricemia.http://dx.doi.org/10.1155/2010/930757 |
| spellingShingle | Ngoc Minh Pham Daigo Yoshida Makiko Morita Guang Yin Kengo Toyomura Keizo Ohnaka Ryoichi Takayanagi Suminori Kono The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years Journal of Nutrition and Metabolism |
| title | The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years |
| title_full | The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years |
| title_fullStr | The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years |
| title_full_unstemmed | The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years |
| title_short | The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years |
| title_sort | relation of coffee consumption to serum uric acid in japanese men and women aged 49 76 years |
| url | http://dx.doi.org/10.1155/2010/930757 |
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