Behçet’s disease in pregnancy: a case report and literature review
Abstract Background Behçet’s disease (BD) during pregnancy is a relatively rare condition, and there are currently no established guidelines for its management. The effects of BD on both mothers and children remain unclear. In this paper, we present the diagnostic and treatment processes for a patie...
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BMC
2025-01-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | https://doi.org/10.1186/s12884-024-07063-0 |
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| author | Xiangyue Li Xuemei Huang Xiaolan Yu |
| author_facet | Xiangyue Li Xuemei Huang Xiaolan Yu |
| author_sort | Xiangyue Li |
| collection | DOAJ |
| description | Abstract Background Behçet’s disease (BD) during pregnancy is a relatively rare condition, and there are currently no established guidelines for its management. The effects of BD on both mothers and children remain unclear. In this paper, we present the diagnostic and treatment processes for a patient with BD during pregnancy. Case presentation A 20-year-old woman, gravida 2, para 1, presented to our inpatient department with recurrent oral and genital ulcers at 28 weeks and 3 days of gestation. Given the complexity of the patient’s condition, we initiated the first multidisciplinary consultation to establish appropriate treatment regimens. However, the initial treatment was ineffective, and the patient experienced a fever for four days. Consequently, we conducted a second multidisciplinary consultation. The final treatment regimen included azithromycin, hydroxychloroquine, prednisone, and low-molecular-weight heparin calcium. The clinical symptoms resolved, and the female neonate was delivered successfully. No relapse was observed during the four-month follow-up. Conclusions The critical issues in treatment involve ensuring medication safety for pregnant women and preventing adverse pregnancy outcomes. Notably, one potential cause of adverse pregnancy outcomes in individuals with BD is vasculopathy, which necessitates prompt treatment with anticoagulant therapy. Obstetricians should closely monitor disease progression and remain vigilant for complications in order to minimize adverse outcomes during pregnancy. |
| format | Article |
| id | doaj-art-a1a3abf4aebc473eab9a30244ed144df |
| institution | Kabale University |
| issn | 1471-2393 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj-art-a1a3abf4aebc473eab9a30244ed144df2025-01-26T12:56:59ZengBMCBMC Pregnancy and Childbirth1471-23932025-01-012511710.1186/s12884-024-07063-0Behçet’s disease in pregnancy: a case report and literature reviewXiangyue Li0Xuemei Huang1Xiaolan Yu2Department of Obstetrics and Gynecology, Southwest Medical UniversityDepartment of Oncology and Hematology, Southwest Medical UniversityDepartment of Obstetrics and Gynecology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical UniversityAbstract Background Behçet’s disease (BD) during pregnancy is a relatively rare condition, and there are currently no established guidelines for its management. The effects of BD on both mothers and children remain unclear. In this paper, we present the diagnostic and treatment processes for a patient with BD during pregnancy. Case presentation A 20-year-old woman, gravida 2, para 1, presented to our inpatient department with recurrent oral and genital ulcers at 28 weeks and 3 days of gestation. Given the complexity of the patient’s condition, we initiated the first multidisciplinary consultation to establish appropriate treatment regimens. However, the initial treatment was ineffective, and the patient experienced a fever for four days. Consequently, we conducted a second multidisciplinary consultation. The final treatment regimen included azithromycin, hydroxychloroquine, prednisone, and low-molecular-weight heparin calcium. The clinical symptoms resolved, and the female neonate was delivered successfully. No relapse was observed during the four-month follow-up. Conclusions The critical issues in treatment involve ensuring medication safety for pregnant women and preventing adverse pregnancy outcomes. Notably, one potential cause of adverse pregnancy outcomes in individuals with BD is vasculopathy, which necessitates prompt treatment with anticoagulant therapy. Obstetricians should closely monitor disease progression and remain vigilant for complications in order to minimize adverse outcomes during pregnancy.https://doi.org/10.1186/s12884-024-07063-0Behçet’s diseasePregnancyAnticoagulant therapy |
| spellingShingle | Xiangyue Li Xuemei Huang Xiaolan Yu Behçet’s disease in pregnancy: a case report and literature review BMC Pregnancy and Childbirth Behçet’s disease Pregnancy Anticoagulant therapy |
| title | Behçet’s disease in pregnancy: a case report and literature review |
| title_full | Behçet’s disease in pregnancy: a case report and literature review |
| title_fullStr | Behçet’s disease in pregnancy: a case report and literature review |
| title_full_unstemmed | Behçet’s disease in pregnancy: a case report and literature review |
| title_short | Behçet’s disease in pregnancy: a case report and literature review |
| title_sort | behcet s disease in pregnancy a case report and literature review |
| topic | Behçet’s disease Pregnancy Anticoagulant therapy |
| url | https://doi.org/10.1186/s12884-024-07063-0 |
| work_keys_str_mv | AT xiangyueli behcetsdiseaseinpregnancyacasereportandliteraturereview AT xuemeihuang behcetsdiseaseinpregnancyacasereportandliteraturereview AT xiaolanyu behcetsdiseaseinpregnancyacasereportandliteraturereview |