Medical treatment prior to micro-TESE
Except in cases of hypogonadotropic hypogonadism, the use of medical therapy before microsurgical testicular sperm extraction (micro-TESE) is controversial. In some studies, hormone therapy has been shown to improve the possibility of sperm retrieval during micro-TESE and even lead to the presence o...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-05-01
|
| Series: | Asian Journal of Andrology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/aja202492 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849694695778680832 |
|---|---|
| author | Sujoy Dasgupta Thanh Sang Le Amarnath Rambhatla Rupin Shah Ashok Agarwal |
| author_facet | Sujoy Dasgupta Thanh Sang Le Amarnath Rambhatla Rupin Shah Ashok Agarwal |
| author_sort | Sujoy Dasgupta |
| collection | DOAJ |
| description | Except in cases of hypogonadotropic hypogonadism, the use of medical therapy before microsurgical testicular sperm extraction (micro-TESE) is controversial. In some studies, hormone therapy has been shown to improve the possibility of sperm retrieval during micro-TESE and even lead to the presence of sperm in the ejaculate in some cases, thereby obviating the need for micro-TESE. However, their routine use before micro-TESE in cases of nonobstructive azoospermia (NOA) being associated with hypergonadotropic hypogonadism and eugonadism (normogonadotropic condition) has not been supported with robust evidence. In this review, we discuss different types of medical therapy used before micro-TESE for NOA, their risks and benefits, and the available evidence surrounding their use in this setting. |
| format | Article |
| id | doaj-art-a1a345e7f1a24c13b092a4a2d2067d06 |
| institution | DOAJ |
| issn | 1008-682X 1745-7262 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Andrology |
| spelling | doaj-art-a1a345e7f1a24c13b092a4a2d2067d062025-08-20T03:19:59ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622025-05-0127334235410.4103/aja202492Medical treatment prior to micro-TESESujoy DasguptaThanh Sang LeAmarnath RambhatlaRupin ShahAshok AgarwalExcept in cases of hypogonadotropic hypogonadism, the use of medical therapy before microsurgical testicular sperm extraction (micro-TESE) is controversial. In some studies, hormone therapy has been shown to improve the possibility of sperm retrieval during micro-TESE and even lead to the presence of sperm in the ejaculate in some cases, thereby obviating the need for micro-TESE. However, their routine use before micro-TESE in cases of nonobstructive azoospermia (NOA) being associated with hypergonadotropic hypogonadism and eugonadism (normogonadotropic condition) has not been supported with robust evidence. In this review, we discuss different types of medical therapy used before micro-TESE for NOA, their risks and benefits, and the available evidence surrounding their use in this setting.https://journals.lww.com/10.4103/aja202492aromatase inhibitorsgonadotropinsmale infertilitymicrosurgical testicular sperm extractionnonobstructive azoospermiaselective estrogen receptor modulatorssuccessful sperm retrieval |
| spellingShingle | Sujoy Dasgupta Thanh Sang Le Amarnath Rambhatla Rupin Shah Ashok Agarwal Medical treatment prior to micro-TESE Asian Journal of Andrology aromatase inhibitors gonadotropins male infertility microsurgical testicular sperm extraction nonobstructive azoospermia selective estrogen receptor modulators successful sperm retrieval |
| title | Medical treatment prior to micro-TESE |
| title_full | Medical treatment prior to micro-TESE |
| title_fullStr | Medical treatment prior to micro-TESE |
| title_full_unstemmed | Medical treatment prior to micro-TESE |
| title_short | Medical treatment prior to micro-TESE |
| title_sort | medical treatment prior to micro tese |
| topic | aromatase inhibitors gonadotropins male infertility microsurgical testicular sperm extraction nonobstructive azoospermia selective estrogen receptor modulators successful sperm retrieval |
| url | https://journals.lww.com/10.4103/aja202492 |
| work_keys_str_mv | AT sujoydasgupta medicaltreatmentpriortomicrotese AT thanhsangle medicaltreatmentpriortomicrotese AT amarnathrambhatla medicaltreatmentpriortomicrotese AT rupinshah medicaltreatmentpriortomicrotese AT ashokagarwal medicaltreatmentpriortomicrotese |