Oral Verruciform Xanthoma: A Case Report and Literature Review
Verruciform xanthoma is a benign mucocutaneous, uncommon, nonsymptomatic lesion of uncertain etiopathology, which occurs mostly on the oral mucosa of middle-aged individuals. Histopathologically, VX is diagnosed by presence of lipid-laden foam cells in papillary region of connective tissue. A 60-yea...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2013/528967 |
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| author | Akshay Shetty Kourosh Nakhaei Yogesh Lakkashetty Maryam Mohseni Iman Mohebatzadeh |
| author_facet | Akshay Shetty Kourosh Nakhaei Yogesh Lakkashetty Maryam Mohseni Iman Mohebatzadeh |
| author_sort | Akshay Shetty |
| collection | DOAJ |
| description | Verruciform xanthoma is a benign mucocutaneous, uncommon, nonsymptomatic lesion of uncertain etiopathology, which occurs mostly on the oral mucosa of middle-aged individuals. Histopathologically, VX is diagnosed by presence of lipid-laden foam cells in papillary region of connective tissue. A 60-year-old male patient presented with a painless growth on the left buccal mucosa. On clinical examination a yellowish white exophytic lesion, measuring 11 × 7 mm in size, was found, which was cauliflower-shaped on inspection and painless on palpation. Histopathological examination revealed varying degrees of surface parakeratosis and the accumulation of numerous foam cells in the connective tissue papillae among the uniformly elongated epithelial ridges. On immunohistochemical staining, there was a neutrophilic infiltrate of the epidermis with CD68 positive xanthoma cells restricted to the papillary dermis, mixed with other chronic inflammatory cells. |
| format | Article |
| id | doaj-art-a1a001d0e5834c4a8d58bd990da036e7 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-a1a001d0e5834c4a8d58bd990da036e72025-02-03T01:28:53ZengWileyCase Reports in Dentistry2090-64472090-64552013-01-01201310.1155/2013/528967528967Oral Verruciform Xanthoma: A Case Report and Literature ReviewAkshay Shetty0Kourosh Nakhaei1Yogesh Lakkashetty2Maryam Mohseni3Iman Mohebatzadeh4Department of Oral and Maxillofacial Surgery, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032, IndiaSri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032, IndiaDepartment of Oral and Maxillofacial Pathology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032, IndiaSri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032, IndiaSri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032, IndiaVerruciform xanthoma is a benign mucocutaneous, uncommon, nonsymptomatic lesion of uncertain etiopathology, which occurs mostly on the oral mucosa of middle-aged individuals. Histopathologically, VX is diagnosed by presence of lipid-laden foam cells in papillary region of connective tissue. A 60-year-old male patient presented with a painless growth on the left buccal mucosa. On clinical examination a yellowish white exophytic lesion, measuring 11 × 7 mm in size, was found, which was cauliflower-shaped on inspection and painless on palpation. Histopathological examination revealed varying degrees of surface parakeratosis and the accumulation of numerous foam cells in the connective tissue papillae among the uniformly elongated epithelial ridges. On immunohistochemical staining, there was a neutrophilic infiltrate of the epidermis with CD68 positive xanthoma cells restricted to the papillary dermis, mixed with other chronic inflammatory cells.http://dx.doi.org/10.1155/2013/528967 |
| spellingShingle | Akshay Shetty Kourosh Nakhaei Yogesh Lakkashetty Maryam Mohseni Iman Mohebatzadeh Oral Verruciform Xanthoma: A Case Report and Literature Review Case Reports in Dentistry |
| title | Oral Verruciform Xanthoma: A Case Report and Literature Review |
| title_full | Oral Verruciform Xanthoma: A Case Report and Literature Review |
| title_fullStr | Oral Verruciform Xanthoma: A Case Report and Literature Review |
| title_full_unstemmed | Oral Verruciform Xanthoma: A Case Report and Literature Review |
| title_short | Oral Verruciform Xanthoma: A Case Report and Literature Review |
| title_sort | oral verruciform xanthoma a case report and literature review |
| url | http://dx.doi.org/10.1155/2013/528967 |
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