Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature
Riedel's thyroiditis is a very rare inflammatory condition. It affects not only the thyroid gland but also the adjacent vital structures. It may also be associated with different forms of systemic fibrotic disorders. The exact etiology is unknown, but currently, the most favorable opinion is th...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2021/5185259 |
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| author | Yassine Er-Rahali Mohammed Massine El Hammoumi Jad Issouani Colna Antonio Nfad Souad El Moussaoui El Hassane Kabiri Ahmed Anass Guerboub |
| author_facet | Yassine Er-Rahali Mohammed Massine El Hammoumi Jad Issouani Colna Antonio Nfad Souad El Moussaoui El Hassane Kabiri Ahmed Anass Guerboub |
| author_sort | Yassine Er-Rahali |
| collection | DOAJ |
| description | Riedel's thyroiditis is a very rare inflammatory condition. It affects not only the thyroid gland but also the adjacent vital structures. It may also be associated with different forms of systemic fibrotic disorders. The exact etiology is unknown, but currently, the most favorable opinion is that it is a localized form of the systemic fibrotic process. We report the case of a 38-year-old woman, presented with a 10-month history of progressive hypothyroidism, dysphonia, and dysphagia. A Doppler ultrasound study revealed massive thyroid enlargement with multiple Eu TIRADS 3 and 4 nodules. Fine needle aspiration was noncontributive on two occasions. A hard subtotal thyroidectomy was performed. Pathological study confirmed Riedel's thyroiditis with the presence of IgG4 antibodies in immunohistochemistry. The patient was successfully treated with levothyroxine replacement and corticosteroid therapy with rapid resolution of obstructive symptoms. The case descriptions highlight the diagnostic challenge of this disease, describe the response to surgical management and corticosteroid therapy, and give a short review of the subject. |
| format | Article |
| id | doaj-art-a19ab79e04984ad59edaba6120ca10af |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-a19ab79e04984ad59edaba6120ca10af2025-02-03T05:43:48ZengWileyCase Reports in Endocrinology2090-65012090-651X2021-01-01202110.1155/2021/51852595185259Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the LiteratureYassine Er-Rahali0Mohammed Massine El Hammoumi1Jad Issouani2Colna Antonio Nfad3Souad El Moussaoui4El Hassane Kabiri5Ahmed Anass Guerboub6Endocrinology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, MoroccoThoracic Surgery Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, MoroccoEndocrinology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, MoroccoEndocrinology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, MoroccoEndocrinology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, MoroccoThoracic Surgery Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, MoroccoEndocrinology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, MoroccoRiedel's thyroiditis is a very rare inflammatory condition. It affects not only the thyroid gland but also the adjacent vital structures. It may also be associated with different forms of systemic fibrotic disorders. The exact etiology is unknown, but currently, the most favorable opinion is that it is a localized form of the systemic fibrotic process. We report the case of a 38-year-old woman, presented with a 10-month history of progressive hypothyroidism, dysphonia, and dysphagia. A Doppler ultrasound study revealed massive thyroid enlargement with multiple Eu TIRADS 3 and 4 nodules. Fine needle aspiration was noncontributive on two occasions. A hard subtotal thyroidectomy was performed. Pathological study confirmed Riedel's thyroiditis with the presence of IgG4 antibodies in immunohistochemistry. The patient was successfully treated with levothyroxine replacement and corticosteroid therapy with rapid resolution of obstructive symptoms. The case descriptions highlight the diagnostic challenge of this disease, describe the response to surgical management and corticosteroid therapy, and give a short review of the subject.http://dx.doi.org/10.1155/2021/5185259 |
| spellingShingle | Yassine Er-Rahali Mohammed Massine El Hammoumi Jad Issouani Colna Antonio Nfad Souad El Moussaoui El Hassane Kabiri Ahmed Anass Guerboub Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature Case Reports in Endocrinology |
| title | Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature |
| title_full | Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature |
| title_fullStr | Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature |
| title_full_unstemmed | Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature |
| title_short | Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature |
| title_sort | reidel s thyroiditis a diagnostic and management challenge a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2021/5185259 |
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