Macular Thickness, Foveal Volume, and Choroidal Thickness in Amblyopic Eyes and Their Relationships to the Treatment Outcome
Purpose. To assess the correlations between the retinal/choroidal structure and the treatment outcomes of amblyopic children. Methods. This study enrolled eyes with amblyopia resulting from strabismus, anisometropia, or ametropia. All patients underwent detailed eye examinations, including spectral...
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2018-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2018/1967621 |
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| author | Chun-Hsiu Liu Sherine Jue Ong Chung-Ying Huang Wei-Chi Wu Ling-Yuh Kao Meng-Ling Yang |
| author_facet | Chun-Hsiu Liu Sherine Jue Ong Chung-Ying Huang Wei-Chi Wu Ling-Yuh Kao Meng-Ling Yang |
| author_sort | Chun-Hsiu Liu |
| collection | DOAJ |
| description | Purpose. To assess the correlations between the retinal/choroidal structure and the treatment outcomes of amblyopic children. Methods. This study enrolled eyes with amblyopia resulting from strabismus, anisometropia, or ametropia. All patients underwent detailed eye examinations, including spectral domain optical coherence tomography (SD-OCT) scan. All of the subjects received amblyopic treatment and were divided into 2 groups after 6 months of follow-up: the recovered amblyopic group with a best-corrected visual acuity (BCVA) ≥0.8 and the persistent amblyopic group with a BCVA <0.8 on the Landolt C chart. Results. Forty-four amblyopic children were included, of which 26 were in the recovered amblyopic group after 6 months of follow-up. The patients with strabismic anisometropic amblyopia and severe amblyopia (initial VA ≤ 0.3) were significantly predisposed to developing persistent amblyopia (P=0.049 and P<0.001, respectively). After correcting with Littmann’s formula, the thickness and volume of the parafoveal and perifoveal retinal regions in the persistent amblyopia group did not show significant differences with the recovered amblyopia group. Conclusions. The initial severity of amblyopia and the type of amblyopia were the risk factors related to the poor outcome of amblyopic treatment. The foveal thickness, foveal volume, and choroidal thickness were not associated with the treatment outcome. |
| format | Article |
| id | doaj-art-a1962835319247cd8735a24ebd581490 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-a1962835319247cd8735a24ebd5814902025-02-03T05:58:39ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/19676211967621Macular Thickness, Foveal Volume, and Choroidal Thickness in Amblyopic Eyes and Their Relationships to the Treatment OutcomeChun-Hsiu Liu0Sherine Jue Ong1Chung-Ying Huang2Wei-Chi Wu3Ling-Yuh Kao4Meng-Ling Yang5Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5, Fuhsing Street, Kweishan, Taoyuan 333, TaiwanChing Ming Eye Clinic, No. 32, Zhongshan 2nd Rd., Luzhou, New Taipei 247, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5, Fuhsing Street, Kweishan, Taoyuan 333, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5, Fuhsing Street, Kweishan, Taoyuan 333, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5, Fuhsing Street, Kweishan, Taoyuan 333, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5, Fuhsing Street, Kweishan, Taoyuan 333, TaiwanPurpose. To assess the correlations between the retinal/choroidal structure and the treatment outcomes of amblyopic children. Methods. This study enrolled eyes with amblyopia resulting from strabismus, anisometropia, or ametropia. All patients underwent detailed eye examinations, including spectral domain optical coherence tomography (SD-OCT) scan. All of the subjects received amblyopic treatment and were divided into 2 groups after 6 months of follow-up: the recovered amblyopic group with a best-corrected visual acuity (BCVA) ≥0.8 and the persistent amblyopic group with a BCVA <0.8 on the Landolt C chart. Results. Forty-four amblyopic children were included, of which 26 were in the recovered amblyopic group after 6 months of follow-up. The patients with strabismic anisometropic amblyopia and severe amblyopia (initial VA ≤ 0.3) were significantly predisposed to developing persistent amblyopia (P=0.049 and P<0.001, respectively). After correcting with Littmann’s formula, the thickness and volume of the parafoveal and perifoveal retinal regions in the persistent amblyopia group did not show significant differences with the recovered amblyopia group. Conclusions. The initial severity of amblyopia and the type of amblyopia were the risk factors related to the poor outcome of amblyopic treatment. The foveal thickness, foveal volume, and choroidal thickness were not associated with the treatment outcome.http://dx.doi.org/10.1155/2018/1967621 |
| spellingShingle | Chun-Hsiu Liu Sherine Jue Ong Chung-Ying Huang Wei-Chi Wu Ling-Yuh Kao Meng-Ling Yang Macular Thickness, Foveal Volume, and Choroidal Thickness in Amblyopic Eyes and Their Relationships to the Treatment Outcome Journal of Ophthalmology |
| title | Macular Thickness, Foveal Volume, and Choroidal Thickness in Amblyopic Eyes and Their Relationships to the Treatment Outcome |
| title_full | Macular Thickness, Foveal Volume, and Choroidal Thickness in Amblyopic Eyes and Their Relationships to the Treatment Outcome |
| title_fullStr | Macular Thickness, Foveal Volume, and Choroidal Thickness in Amblyopic Eyes and Their Relationships to the Treatment Outcome |
| title_full_unstemmed | Macular Thickness, Foveal Volume, and Choroidal Thickness in Amblyopic Eyes and Their Relationships to the Treatment Outcome |
| title_short | Macular Thickness, Foveal Volume, and Choroidal Thickness in Amblyopic Eyes and Their Relationships to the Treatment Outcome |
| title_sort | macular thickness foveal volume and choroidal thickness in amblyopic eyes and their relationships to the treatment outcome |
| url | http://dx.doi.org/10.1155/2018/1967621 |
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