Prediction of biological activity of spiroquinazolone derivatives as protein kinase inhibitors FGFR1 and CK2
The purpose. The search for FGFR1 and CK2 protein kinase inhibitors were performed among spiroquinazolone derivatives using receptor-oriented virtual screening and in vitro biochemical testing using the human CK2 kinase domain. Materials and methods. The docking was performed at ATP binding sites...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Zaporizhzhia State Medical and Pharmaceutical University
2020-05-01
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| Series: | Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki |
| Subjects: | |
| Online Access: | http://pharmed.zsmu.edu.ua/article/view/198175/199126 |
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