Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT Scans

Automatic detection of lung nodules is an important problem in computer analysis of chest radiographs. In this paper, we propose a novel algorithm for isolating lung abnormalities (nodules) from spiral chest low-dose CT (LDCT) scans. The proposed algorithm consists of three main steps. The first ste...

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Main Authors: Ayman El-Baz, Ahmed Elnakib, Mohamed Abou El-Ghar, Georgy Gimel'farb, Robert Falk, Aly Farag
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2013/517632
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author Ayman El-Baz
Ahmed Elnakib
Mohamed Abou El-Ghar
Georgy Gimel'farb
Robert Falk
Aly Farag
author_facet Ayman El-Baz
Ahmed Elnakib
Mohamed Abou El-Ghar
Georgy Gimel'farb
Robert Falk
Aly Farag
author_sort Ayman El-Baz
collection DOAJ
description Automatic detection of lung nodules is an important problem in computer analysis of chest radiographs. In this paper, we propose a novel algorithm for isolating lung abnormalities (nodules) from spiral chest low-dose CT (LDCT) scans. The proposed algorithm consists of three main steps. The first step isolates the lung nodules, arteries, veins, bronchi, and bronchioles from the surrounding anatomical structures. The second step detects lung nodules using deformable 3D and 2D templates describing typical geometry and gray-level distribution within the nodules of the same type. The detection combines the normalized cross-correlation template matching and a genetic optimization algorithm. The final step eliminates the false positive nodules (FPNs) using three features that robustly define the true lung nodules. Experiments with 200 CT data sets show that the proposed approach provided comparable results with respect to the experts.
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institution Kabale University
issn 1687-4188
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language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series International Journal of Biomedical Imaging
spelling doaj-art-a160c4efc2434757a660e31d118e2a292025-02-03T05:45:36ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962013-01-01201310.1155/2013/517632517632Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT ScansAyman El-Baz0Ahmed Elnakib1Mohamed Abou El-Ghar2Georgy Gimel'farb3Robert Falk4Aly Farag5Bioimaging Laboratory, Department of Bioengineering, University of Louisville, Louisville, KY 40292, USABioimaging Laboratory, Department of Bioengineering, University of Louisville, Louisville, KY 40292, USAUrology and Nephrology Department, University of Mansoura, Mansoura 35516, EgyptDepartment of Computer Science, The University of Auckland 1142, Auckland, New ZealandMedical Imaging Division, Jewish Hospital, Louisville, KY 40202, USAElectrical and Computer Engineering Department, University of Louisville, KY 40292, USAAutomatic detection of lung nodules is an important problem in computer analysis of chest radiographs. In this paper, we propose a novel algorithm for isolating lung abnormalities (nodules) from spiral chest low-dose CT (LDCT) scans. The proposed algorithm consists of three main steps. The first step isolates the lung nodules, arteries, veins, bronchi, and bronchioles from the surrounding anatomical structures. The second step detects lung nodules using deformable 3D and 2D templates describing typical geometry and gray-level distribution within the nodules of the same type. The detection combines the normalized cross-correlation template matching and a genetic optimization algorithm. The final step eliminates the false positive nodules (FPNs) using three features that robustly define the true lung nodules. Experiments with 200 CT data sets show that the proposed approach provided comparable results with respect to the experts.http://dx.doi.org/10.1155/2013/517632
spellingShingle Ayman El-Baz
Ahmed Elnakib
Mohamed Abou El-Ghar
Georgy Gimel'farb
Robert Falk
Aly Farag
Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT Scans
International Journal of Biomedical Imaging
title Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT Scans
title_full Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT Scans
title_fullStr Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT Scans
title_full_unstemmed Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT Scans
title_short Automatic Detection of 2D and 3D Lung Nodules in Chest Spiral CT Scans
title_sort automatic detection of 2d and 3d lung nodules in chest spiral ct scans
url http://dx.doi.org/10.1155/2013/517632
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